Detection of antibodies to human T-lymphotropic viruses type I and III in Japanese hemophiliacs. NLM AIDSLINE Important note: Information in this article was accurate in 1986. The state of the art may have changed since the publication date.

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Detection of antibodies to human T-lymphotropic viruses type I and III in Japanese hemophiliacs.

AIDS Res. 1983-84;1(5):353-8. Unique Identifier : AIDSLINE MED/86242466
Koyanagi Y; Kobayashi S; Harada S; Kikukawa R; Yamamoto N; Watanabe K; Okino F; Kajii T


Abstract: Sera of 65 hemophiliacs, 85 hemodialysis patients and 304 healthy volunteer blood donors in Japan were tested for antibodies against both HTLV-I and -III by an indirect immunofluorescence and radioimmunoprecipitation assay. The results showed that 10 (15.4%) of the hemophiliacs were anti-HTLV-III positive, while all other subjects were anti-HTLV-III negative. All groups contained subjects positive for anti-HTLV-I. The prevalence of the antibody in the hemophiliacs (17.4%) and hemodialysis patients (9.4%) was significantly high as compared to that of healthy controls (1%).
Keywords: Adolescence Adult Antibodies, Viral/*ANALYSIS Child Child, Preschool Comparative Study Fluorescent Antibody Technique Hemodialysis Hemophilia/*IMMUNOLOGY Human HTLV-BLV Viruses/*IMMUNOLOGY Japan Middle Age Precipitin Tests Support, Non-U.S. Gov't JOURNAL ARTICLE

KWDadolescenceadultantibodies,viral/KWDanalysischildchild,preschoolcomparativestudyfluorescentantibodytechniquehemodialysishemophilia/KWDimmunologyhumanhtlv-blvviruses/KWDimmunologyjapanmiddleageprecipitintestssupport,non-uKWDsKWDgov'tjournalarticle
861030
M86A0291


Copyright © 1986 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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