Antibodies to the AIDS-associated retrovirus in hemophiliacs and other individuals from southern Spain: lack of correlation with lymphocytes sub-populations. NLM AIDSLINE Important note: Information in this article was accurate in 1986. The state of the art may have changed since the publication date.

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Antibodies to the AIDS-associated retrovirus in hemophiliacs and other individuals from southern Spain: lack of correlation with lymphocytes sub-populations.

AIDS Res. 1984-85;1(6):439-45. Unique Identifier : AIDSLINE MED/86242474
Ollero M; Leal M; Wichmann I; Lissen E; Levy JA

Abstract: Exposure to the AIDS-associated retrovirus (ARV) has been observed in 54 hemophiliacs in Southern Spain who have received commercial coagulation factors manufactured in the United States. Contact with ARV could be detected in some sera collected in 1982. Frequency among asymptomatic hemophiliacs was 44%, in individuals with lymphadenopathy syndrome 71%, and 2 AIDS cases were seropositive. Evidence for exposure to ARV did not correlate with changes in the lymphocyte populations or in the clinical condition of the patients. Only the amount of factor received distinguished the seropositive and the seronegative groups of hemophiliacs. Exposure to ARV was also detected in sera from homosexual men and I.V. drug addicts. The results indicate that members of AIDS risk groups in Spain have had contact with the AIDS retrovirus.
Keywords: Antibodies, Viral/ANALYSIS/*IMMUNOLOGY Factor IX/ADMINISTRATION & DOSAGE Factor VIII/ADMINISTRATION & DOSAGE Hemophilia/*BLOOD Homosexuality Human HTLV-BLV Viruses/*IMMUNOLOGY Immunoblastic Lymphadenopathy/BLOOD Lymphocytes/*CLASSIFICATION Male Risk Spain Substance Dependence Support, U.S. Gov't, P.H.S. T-Lymphocytes, Helper-Inducer/CYTOLOGY T-Lymphocytes, Suppressor-Effector/CYTOLOGY JOURNAL ARTICLE

KWDantibodies,viral/analysis/KWDimmunologyfactorix/administration&dosagefactorviii/administration&dosagehemophilia/KWDbloodhomosexualityhumanhtlv-blvviruses/KWDimmunologyimmunoblasticlymphadenopathy/bloodlymphocytes/KWDclassificationmaleriskspainsubstancedependencesupport,uKWDsKWDgov't,pKWDhKWDsKWDt-lymphocytes,helper-inducer/cytologyt-lymphocytes,suppressor-effector/cytologyjournalarticle
861030
M86A0287

Copyright © 1986 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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