Pathogens in children with severe combined immune deficiency disease or AIDS. NLM AIDSLINE Important note: Information in this article was accurate in 1986. The state of the art may have changed since the publication date.

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Pathogens in children with severe combined immune deficiency disease or AIDS.

Can Med Assoc J. 1986 Jul 1;135(1):33-8. Unique Identifier : AIDSLINE MED/86244567
Lauzon D; Delage G; Brochu P; Michaud J; Jasmin G; Joncas JH; Lapointe N

Abstract: We evaluated the frequency and severity of illnesses caused by various microbial pathogens in 15 children with severe combined immune deficiency disease (SCID) and 8 with acquired immune deficiency syndrome (AIDS). There were 35 viral, 23 bacterial, 19 mycotic and 13 parasitic infections. Nineteen of the 23 patients died of infection; Pneumocystis carinii pneumonia, giant-cell pneumonia due to paramyxoviruses and various disseminated viral infections were responsible for most deaths in both groups. The emerging role of paramyxoviruses was illustrated by the fact that they were responsible for giant-cell pneumonia in seven patients. Viral enteric infections were frequent in both groups. The variety of infectious microorganisms and the severity of resulting illnesses in the patients with AIDS were similar to those in the patients with SCID.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS Adenosine Deaminase/DEFICIENCY Bacterial Infections/*COMPLICATIONS Child, Preschool Female Gastrointestinal Diseases/COMPLICATIONS Human Immunologic Deficiency Syndromes/*COMPLICATIONS Infant Male Mycoses/*COMPLICATIONS Parasitic Diseases/*COMPLICATIONS Respiratory Tract Infections/COMPLICATIONS Virus Diseases/*COMPLICATIONS JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDcomplicationsadenosinedeaminase/deficiencybacterialinfections/KWDcomplicationschild,preschoolfemalegastrointestinaldiseases/complicationshumanimmunologicdeficiencysyndromes/KWDcomplicationsinfantmalemycoses/KWDcomplicationsparasiticdiseases/KWDcomplicationsrespiratorytractinfections/complicationsvirusdiseases/KWDcomplicationsjournalarticle
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M86A0282

Copyright © 1986 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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