Tuberculosis as a manifestation of the acquired immunodeficiency syndrome (AIDS). NLM AIDSLINE Important note: Information in this article was accurate in 1986. The state of the art may have changed since the publication date.

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Tuberculosis as a manifestation of the acquired immunodeficiency syndrome (AIDS).

JAMA. 1986 Jul 18;256(3):362-6. Unique Identifier : AIDSLINE MED/86254559
Sunderam G; McDonald RJ; Maniatis T; Oleske J; Kapila R; Reichman LB

Abstract: Tuberculosis has not been well documented as a complication of the acquired immunodeficiency syndrome (AIDS). We studied 48 cases of mycobacterial diseases among a group of 136 adult patients with AIDS over a 43-month period. Twenty-nine of them had severe and unusual manifestations of disease due to Mycobacterium tuberculosis, predominantly extrapulmonary and disseminated. Tuberculosis was more common among Haitians (4/8) and intravenous drug abusers (24/102) than among homosexuals who did not abuse drugs (0/22). Twelve of 21 patients with tuberculosis who were treated responded well, whereas three developed progressive disease indicative of treatment failure. Severe and unusual presentation of overwhelming tuberculosis in appropriate clinical circumstances may be considered an infection predictive of the presence of AIDS.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS Adult Female Granuloma/ETIOLOGY Haiti/ETHNOLOGY Homosexuality Human Male Middle Age Mycobacterium avium Mycobacterium Infections/*ETIOLOGY Mycobacterium Infections, Atypical/*ETIOLOGY Risk Substance Abuse/COMPLICATIONS Tuberculosis/*ETIOLOGY/IMMUNOLOGY/PATHOLOGY JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDcomplicationsadultfemalegranuloma/etiologyhaiti/ethnologyhomosexualityhumanmalemiddleagemycobacteriumaviummycobacteriuminfections/KWDetiologymycobacteriuminfections,atypical/KWDetiologyrisksubstanceabuse/complicationstuberculosis/KWDetiology/immunology/pathologyjournalarticle
861030
M86A0261

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