Important note: Information in this article was accurate in 1986. The state of the art may have changed since the publication date.
RNA TUMOR VIRUSES, ONCOGENES, HUMAN CANCER AND AIDS: ON THE FRONTIERS OF UNDERSTANDING
Dev Oncol; 28:1-409 1985. Unique Identifier : AIDSLINE ICDB/86621720 Anonymous; No affiliation given
Abstract:
This volume presents the proceedings of the International Conference on RNA Tumor Viruses in Human Cancer, held in Denver, Colorado on 10-14 June 1984. A section on molecular genetics of the RNA tumor viruses includes papers dealing with the following topics: the myc genetic element, viral and cellular fos gene, P21 ras transforming protein, protein phosphorylation of tyrosine in normal and transformed cells, activation of a gene coding for a normal human growth factor to one with transforming properties, and cell cycle control of c-myc expression. A section on endogenous retrovirus sequences in human cells includes papers dealing with new human endogenous retroviral genes, human endogenous type C retroviral DNAs, and the human endogenous provirus ERV3. A section on molecular biology of human cancer includes papers dealing with a molecular basis of human B-cell neoplasia, transforming genes in lymphoid neoplasms, oncogenes in chronic myelocytic leukemia, ras gene expression at the single cell level in human colon and mammary carcinomas, and cancers caused by proto-onc gene. A section on HTLV/LAV, T-cell leukemia, and AIDS includes papers dealing with human T-cell leukemia viruses in T-cell leukemia and AIDS, a novel human lymphotropic retrovirus (LAV) with a role in AIDS, human T-cell leukemia viruses in immunosuppression and AIDS, human retrovirus in AIDS, human RNA and DNA oncogenic viruses in transmissible and malignant diseases, human T-cell leukemia virus antibodies in mycosis fungoides and leukemias and lymphomas, and immunologic functions and the pathogenesis of AIDS. A section on experimental model systems for the study of human neoplasia and related diseases includes papers that deal with experimental studies of the pathogenesis of feline leukemia virus infection, feline leukemia and sarcoma virus, bovine leukemia virus, a new messenger RNA expressed by bovine leukemia virus-infected cells, primate retroviruses and AIDS, molecular comparisons of D-type retroviruses, woodchuck hepatitis virus and hepatitis B virus, and virus-negative cell lines derived from radiation- or chemical-induced T-cell lymphomas in NFS/N mice and subsequent generation of oncogenic virus in such lines. A final section on perspectives includes a paper dealing with molecular biology in the control of human malignancies and a paper dealing with implications for the control of human cancer.
Keywords: Acquired Immunodeficiency Syndrome/*MICROBIOLOGY Animal Human Neoplasms/*MICROBIOLOGY *Oncogenes Retroviridae Retroviridae Infections/*MICROBIOLOGY MONOGRAPH
AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.
Important note: Information in this article was accurate in 1986. The state of the art may have changed since the publication date.
