A COMPARISON OF THE ACQUIRED IMMUNE DEFICIENCY SYNDROME IN MONKEY AND MAN NLM AIDSLINE Important note: Information in this article was accurate in 1986. The state of the art may have changed since the publication date.

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A COMPARISON OF THE ACQUIRED IMMUNE DEFICIENCY SYNDROME IN MONKEY AND MAN

Dev Oncol; 31:171-90 1985. Unique Identifier : AIDSLINE ICDB/86624711
Meyer PR; Osborn KG; USC-Dept. of Pathology, 2025 Zonal Avenue, Los Angeles, CA 90033

Abstract: The acquired immune deficiency syndrome (AIDS) in man and that in the Rhesus-Macaque monkey are discussed under the following headings: AIDS in the human; AIDS in the simian (SAIDS); pathogenesis (lymph node findings in monkey and man); early changes in SAIDS; follicular hyperplasia; lymphocyte depletion; summary of lymph node findings; malignant lymphoma of B-cell origin; the retrovirus (comparison of human T-leukemia virus-III and the SAID retrovirus); and transmission of AIDS. Spontaneous acquired immunodeficiencies occurring among selected humans and in primate colonies throughout the United States have a number of clinical, pathologic, immunologic, and biologic similarities; these include a relatively restricted geographic pattern and opportunistic infections and tumors. More recently a retrovirus has been proposed as the causative factor in both. A pathomechanistic approach to the understanding of the disease syndrome(s) is detailed. (47 Refs)
Keywords: Acquired Immunodeficiency Syndrome/*DIAGNOSIS/MICROBIOLOGY/ TRANSMISSION/VETERINARY Adult Animal B-Lymphocytes Child Comparative Study Female Human Hyperplasia HTLV-BLV Viruses/ANALYSIS Lymph Nodes/*PATHOLOGY Lymphoma/DIAGNOSIS Macaca mulatta Male Monkey Diseases/*DIAGNOSIS/MICROBIOLOGY/TRANSMISSION Retroviridae/ANALYSIS Retroviridae Infections/*DIAGNOSIS/MICROBIOLOGY/TRANSMISSION/ VETERINARY Sarcoma, Kaposi's MEETING PAPER REVIEW

KWDacquiredimmunodeficiencysyndrome/KWDdiagnosis/microbiology/transmission/veterinaryadultanimalb-lymphocyteschildcomparativestudyfemalehumanhyperplasiahtlv-blvviruses/analysislymphnodes/KWDpathologylymphoma/diagnosismacacamulattamalemonkeydiseases/KWDdiagnosis/microbiology/transmissionretroviridae/analysisretroviridaeinfections/KWDdiagnosis/microbiology/transmission/veterinarysarcoma,kaposi'smeetingpaperreview
861130
M86B0238

Copyright © 1986 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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