Acquired immunodeficiency syndrome (AIDS)--apheresis and operative risks. NLM AIDSLINE Important note: Information in this article was accurate in 1986. The state of the art may have changed since the publication date.

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Acquired immunodeficiency syndrome (AIDS)--apheresis and operative risks.

J Clin Apheresis. 1985;2(4):427-40. Unique Identifier : AIDSLINE MED/86059288
Kiprov DD; Lippert R; Sandstrom E; Jones FR; Cohen RJ; Abrams D; Busch DF

Abstract: The removal of immune complexes, autoantibodies and suppressor factors from the circulation of patients with AIDS and AIDS related conditions by plasmapheresis and selective immunoadsorption may play a role as a therapeutic modality in these disorders. Lymphocytapheresis may also be of potential use in AIDS related conditions with presumed autoimmune basis. Perfusion of plasma over immobilized protein A columns is being evaluated as a possible immunomodulatory and antitumor therapy in patients with AIDS related Kaposi's sarcoma. Although apheresis procedures as a therapeutic modality in AIDS related conditions are still at the experimental stage, preliminary results are encouraging. The possible transmission of the disease by blood products presents a health hazard to health workers involved in the field of apheresis. Since the mode of transmission of the disease appears to be similar to hepatitis B, strict hepatitis B precautions should be enforced in every case in which AIDS suspected blood is being processed.
Keywords: Acquired Immunodeficiency Syndrome/COMPLICATIONS/*THERAPY/ TRANSMISSION *Blood Component Removal/ADVERSE EFFECTS/METHODS Hemoperfusion Human Immunity, Cellular Infection/COMPLICATIONS Leukapheresis Male Plasmapheresis Risk Sarcoma, Kaposi's/COMPLICATIONS JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/complications/KWDtherapy/transmissionKWDbloodcomponentremoval/adverseeffects/methodshemoperfusionhumanimmunity,cellularinfection/complicationsleukapheresismaleplasmapheresisrisksarcoma,kaposi's/complicationsjournalarticle
860330
M8630173

Copyright © 1986 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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