VIRAL MECHANISMS OF IMMUNOSUPPRESSION NLM AIDSLINE Important note: Information in this article was accurate in 1986. The state of the art may have changed since the publication date.

Click here to return to AIDSLINE main menu
DonateNow
Print this Article


VIRAL MECHANISMS OF IMMUNOSUPPRESSION

Prog Leukocyte Biol; 1:1-284 1985. Unique Identifier : AIDSLINE ICDB/86620616
Anonymous; No affiliation given

Abstract: This volume consists of papers presented at the workshop on Viral Mechanisms of Immunosuppression, held in Montreal in June, 1984. The papers in section I, on general models of virus-induced immunosuppression, cover the following topics: primary immunodeficiency disorders in man; cytomegalovirus and measles virus as in vitro models for virus-mediated immunosuppression; role of mouse hepatitis virus 3-lymphocyte interaction in coronavirus-induced immunosuppression; adenoviruses in human lymphocytes; human T-cell leukemia virus infection in man; inhibition of T lymphocyte mitogenesis by human T lymphotropic viruses; and acquired, transient immunodeficiency of unknown etiology in anergic surgical patients (pts). The papers in section II, on the effect of infection with herpes virus on immune function, cover the following topics: bovine herpesvirus-1 infection in cattle as a model for viral induced immunosuppression; immunosuppressive effects of Epstein-Barr virus infection; Epstein-Barr virus, immune defects, and lymphoproliferative disorders; cytotoxic cellular immunity and cytomegalovirus; effects of herpes simplex virus infection upon the immune system; and acute thymic atrophy in severe herpes simplex virus type 2 infection. Finally, the papers in section III, on involvement of biological response modifiers in virus-induced immunosuppression, cover the following topics: diminished responsiveness of virus co-incubated lymphocytes to T cell growth factor in breast cancer pts; interaction of natural killer cells and viruses; differential expression of human interferon genes; effects of virus-induced interferons on the immune system; effects of virus infections upon macrophage functions; attempted restoration of in vitro immune function in pts with AIDS; and cells of the immune system as targets of viral infection, and feedback inhibition by suppressor cells and immunoglobulins.
Keywords: Animal Human *Immune Tolerance Virus Diseases/*IMMUNOLOGY Viruses/*IMMUNOLOGY MONOGRAPH

KWDanimalhumanKWDimmunetolerancevirusdiseases/KWDimmunologyviruses/KWDimmunologymonograph
860730
M8670317

Copyright © 1986 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1986. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1986. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .