[Cryptococcus neoformans meningoencephalitis in AIDS] NLM AIDSLINE Important note: Information in this article was accurate in 1986. The state of the art may have changed since the publication date.

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[Cryptococcus neoformans meningoencephalitis in AIDS]

Klin Wochenschr. 1986 Feb 17;64(4):165-72. Unique Identifier : AIDSLINE MED/86173061
Bohle C; Sinn M; Werner E; Staib F

Abstract: The risk for AIDS patients from Cryptococcus neoformans is outlined on the basis of a case report on a 28-year old male patient whose disease was complicated by cryptococcosis. Beside the description of the diagnosis of cryptococcosis (demonstration of the agent and its antigen), epidemiological associations (habitat of Cr. neoformans in fecal matter of birds) and the clinically, mostly not recognized, route of infection via the lungs is stressed. The effective therapy with the combination of amphotericin B and 5-flucytosine, which also in this case has been successful is described from the clinical and microbiological angles. Finally, proposals for the prevention of Cr. neoformans infections in AIDS patients and for a special mycological surveillance directed at this fungus are made.
Keywords: Acquired Immunodeficiency Syndrome/*DIAGNOSIS Adult Amphotericin B/THERAPEUTIC USE Case Report Cryptococcosis/*DIAGNOSIS/DRUG THERAPY Drug Therapy, Combination English Abstract Flucytosine/THERAPEUTIC USE Human Male Meningoencephalitis/*DIAGNOSIS/DRUG THERAPY Risk JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDdiagnosisadultamphotericinb/therapeuticusecasereportcryptococcosis/KWDdiagnosis/drugtherapydrugtherapy,combinationenglishabstractflucytosine/therapeuticusehumanmalemeningoencephalitis/KWDdiagnosis/drugtherapyriskjournalarticle
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M8670262

Copyright © 1986 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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