Multicentric giant lymph node hyperplasia, Kaposi's sarcoma, and lymphoma. NLM AIDSLINE Important note: Information in this article was accurate in 1986. The state of the art may have changed since the publication date.

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Multicentric giant lymph node hyperplasia, Kaposi's sarcoma, and lymphoma.

Arch Pathol Lab Med. 1985 Nov;109(11):1013-8. Unique Identifier : AIDSLINE MED/86024682
Dickson D; Ben-Ezra JM; Reed J; Flax H; Janis R

Abstract: We studied two cases of a recently recognized systemic lymphoproliferative disease with morphological features of Castleman's disease: multicentric giant lymph node hyperplasia. Both patients developed Kaposi's sarcoma and had laboratory evidence of immune abnormalities, including reversed T4 to T8 ratios. One patient's disease had a subacute course with fevers of unknown origin, mucocutaneous candidiasis, and progressive thrombocytopenia, while the other patient's disease had a fulminant course with anemia, thrombocytopenia, and splenic lymphoma. Both patients were elderly, and both died of complications of multicentric giant lymph node hyperplasia.
Keywords: Acquired Immunodeficiency Syndrome/PATHOLOGY Aged Case Report Diagnosis, Differential Female Foot Diseases/COMPLICATIONS/IMMUNOLOGY/PATHOLOGY Human Hyperplasia Immunoglobulins/ANALYSIS Lymph Nodes/*PATHOLOGY Lymphocyte Transformation Lymphoma/*COMPLICATIONS/IMMUNOLOGY/PATHOLOGY Male Omentum/PATHOLOGY Sarcoma, Kaposi's/*COMPLICATIONS/IMMUNOLOGY/PATHOLOGY Skin/PATHOLOGY Skin Neoplasms/*COMPLICATIONS/IMMUNOLOGY/PATHOLOGY Spleen/PATHOLOGY Splenic Neoplasms/*COMPLICATIONS/IMMUNOLOGY/PATHOLOGY JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/pathologyagedcasereportdiagnosis,differentialfemalefootdiseases/complications/immunology/pathologyhumanhyperplasiaimmunoglobulins/analysislymphnodes/KWDpathologylymphocytetransformationlymphoma/KWDcomplications/immunology/pathologymaleomentum/pathologysarcoma,kaposi's/KWDcomplications/immunology/pathologyskin/pathologyskinneoplasms/KWDcomplications/immunology/pathologyspleen/pathologysplenicneoplasms/KWDcomplications/immunology/pathologyjournalarticle
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M8610132

Copyright © 1986 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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