Multicentric giant lymph node hyperplasia. A report of seven cases. NLM AIDSLINE Important note: Information in this article was accurate in 1986. The state of the art may have changed since the publication date.

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Multicentric giant lymph node hyperplasia. A report of seven cases.

Cancer. 1985 Nov 15;56(10):2446-51. Unique Identifier : AIDSLINE MED/86002157
Kessler E

Abstract: Multicentric giant lymph node hyperplasia (MGLH) is a distinct lymphoproliferative disorder, which may terminate in malignant lymphoma. The clinical features and laboratory findings of seven cases are reported here. The histologic changes in lymph nodes were those of giant lymph node hyperplasia, plasma cell type. Immunoperoxidase staining showed intracytoplasmatic polyclonal immunoglobulins. Malignant lymphoma supervened in two cases, one of which was proved by autopsy; in the other there was transformation of a polyclonal gammopathy into a monoclonal one. Two of the patients also developed Kaposi's sarcoma.
Keywords: Aged Female Histocytochemistry Human Hyperplasia/PATHOLOGY Immunoblastic Lymphadenopathy/BLOOD/IMMUNOLOGY/PATHOLOGY Immunoenzyme Techniques Immunoglobulins/ANALYSIS Lymph Nodes/BLOOD SUPPLY/*PATHOLOGY Male Sarcoma, Kaposi's/PATHOLOGY Stains and Staining Submandibular Gland/PATHOLOGY JOURNAL ARTICLE

KWDagedfemalehistocytochemistryhumanhyperplasia/pathologyimmunoblasticlymphadenopathy/blood/immunology/pathologyimmunoenzymetechniquesimmunoglobulins/analysislymphnodes/bloodsupply/KWDpathologymalesarcoma,kaposi's/pathologystainsandstainingsubmandibulargland/pathologyjournalarticle
860130
M8610114

Copyright © 1986 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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