Alterations of functional subsets of T helper and T suppressor cell populations in acquired immunodeficiency syndrome (AIDS) and chronic unexplained lymphadenopathy. NLM AIDSLINE Important note: Information in this article was accurate in 1986. The state of the art may have changed since the publication date.

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Alterations of functional subsets of T helper and T suppressor cell populations in acquired immunodeficiency syndrome (AIDS) and chronic unexplained lymphadenopathy.

J Clin Immunol. 1985 Jul;5(4):269-74. Unique Identifier : AIDSLINE MED/86008800
Nicholson JK; McDougal JS; Spira TJ

Abstract: We have studied the distribution of Leu8 and Ia on T cells of the helper (T4) and suppressor (T8) phenotype in homosexual men with chronic unexplained lymphadenopathy, homosexual men with the acquired immunodeficiency syndrome (AIDS), and homosexual and heterosexual controls. Decreased numbers of helper T cells in lymphadenopathy patients are due to a decrease in the T4:Leu8+ subset, whereas in AIDS patients, both the T4:Leu8+ and the T4:Leu8- subsets were decreased.
Keywords: Acquired Immunodeficiency Syndrome/BLOOD/*IMMUNOLOGY Antibodies, Monoclonal/IMMUNOLOGY Comparative Study Homosexuality Human Leukocyte Count Lymphatic Diseases/BLOOD/*IMMUNOLOGY Male T-Lymphocytes, Helper-Inducer/*CLASSIFICATION/IMMUNOLOGY T-Lymphocytes, Suppressor-Effector/*CLASSIFICATION/IMMUNOLOGY JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/blood/KWDimmunologyantibodies,monoclonal/immunologycomparativestudyhomosexualityhumanleukocytecountlymphaticdiseases/blood/KWDimmunologymalet-lymphocytes,helper-inducer/KWDclassification/immunologyt-lymphocytes,suppressor-effector/KWDclassification/immunologyjournalarticle
860130
M8610099

Copyright © 1986 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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