Thymus biopsy in children with acquired immunodeficiency syndrome. NLM AIDSLINE Important note: Information in this article was accurate in 1986. The state of the art may have changed since the publication date.

Click here to return to AIDSLINE main menu
DonateNow
Print this Article


Thymus biopsy in children with acquired immunodeficiency syndrome.

Arch Pathol Lab Med. 1986 Sep;110(9):837-42. Unique Identifier : AIDSLINE MED/86322392
Joshi VV; Oleske JM; Saad S; Gadol C; Connor E; Bobila R; Minnefor AB

Abstract: Thymic biopsy was done at the time of open lung biopsy in 11 children with acquired immunodeficiency syndrome (AIDS). Precocious involution, involution mimicking dysplasia designated as dysinvolution, and thymitis characterized by lymphomononuclear or plasmacytic infiltration, medullary lymphoid follicles, or medullary multinucleated giant cells were seen. Thymic biopsy is helpful in distinguishing AIDS from certain congenital immunodeficiency disorders. The three different types of thymic lesions may represent progression and/or different expressions of thymic epithelial injury in children with AIDS.
Keywords: Acquired Immunodeficiency Syndrome/*PATHOLOGY Adolescence Adult Biopsy Child Digeorge Syndrome/PATHOLOGY Female Human Inflammation/PATHOLOGY Lung/PATHOLOGY Male Thymus Gland/*PATHOLOGY JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDpathologyadolescenceadultbiopsychilddigeorgesyndrome/pathologyfemalehumaninflammation/pathologylung/pathologymalethymusgland/KWDpathologyjournalarticle
861230
M86C0186

Copyright © 1986 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1986. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1986. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .