Pulmonary Kaposi's sarcoma. Premortem histologic diagnosis. NLM AIDSLINE Important note: Information in this article was accurate in 1986. The state of the art may have changed since the publication date.

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Pulmonary Kaposi's sarcoma. Premortem histologic diagnosis.

Am J Surg Pathol. 1986 May;10(5):301-11. Unique Identifier : AIDSLINE MED/86212776
Purdy LJ; Colby TV; Yousem SA; Battifora H

Abstract: Nine open lung biopsies and nine transbronchial biopsies from 10 patients with pulmonary Kaposi's sarcoma were reviewed to define the pattern of involvement in the lung by Kaposi's sarcoma and to determine the usefulness of transbronchial biopsy in making the diagnosis. There were nine patients with acquired immune deficiency syndrome (AIDS) and one patient with sporadic pulmonary Kaposi's sarcoma. A lymphatic distribution was seen in all cases. A spectrum ranging from distinctive polymorphous cellular infiltrates ultimately interpreted as Kaposi's sarcoma to classic Kaposi's sarcoma was found. Recognition of the former enabled retrospective recognition of Kaposi's sarcoma in four of eight transbronchial bronchial biopsies. The diagnosis of pulmonary Kaposi's sarcoma in one other patient was made solely on the basis of transbronchial biopsy. Eight patients died from pulmonary Kaposi's sarcoma; two patients are alive with extensive pulmonary Kaposi's at last follow-up. We believe that transbronchial biopsy may be useful in establishing a diagnosis of pulmonary Kaposi's sarcoma in many more patients than is generally appreciated.
Keywords: Acquired Immunodeficiency Syndrome/COMPLICATIONS Adult Aged Biopsy Bronchi/PATHOLOGY Diagnosis, Differential Human Lung Neoplasms/*PATHOLOGY Lymphatic System/PATHOLOGY Male Middle Age Sarcoma, Kaposi's/COMPLICATIONS/*PATHOLOGY JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/complicationsadultagedbiopsybronchi/pathologydiagnosis,differentialhumanlungneoplasms/KWDpathologylymphaticsystem/pathologymalemiddleagesarcoma,kaposi's/complications/KWDpathologyjournalarticle
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M8680227

Copyright © 1986 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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