[Acquired immunodeficiency syndrome in a child of Swiss origin whose mother died from AIDS] NLM AIDSLINE Important note: Information in this article was accurate in 1986. The state of the art may have changed since the publication date.

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[Acquired immunodeficiency syndrome in a child of Swiss origin whose mother died from AIDS]

Helv Paediatr Acta. 1985 Sep;40(4):261-76. Unique Identifier : AIDSLINE MED/86085132
Bircher A; Joller-Jemelka HI; Joller PW; Rampini S; Vogt M; Shmerling DH; Briner J; Schupbach J

Abstract: Report of a now 2 8/12-year-old girl, who presented at the age of 8 months with chronic progressive pneumonia, mucocutaneous candidiasis, diarrhea, failure to thrive and a non-progressive paraplegia. The child's mother presented AIDS with pneumocystis carinii pneumonia and progressive general paralysis one year after the beginning of the child's disease and died within a few months. Additional findings in the child include lymphopenia, hyperimmunoglobulinemia, cutaneous anergy and an abnormal T helper/T suppressor cell ratio. HTLV-III antibodies were positive (ELISA and Western blot virus strip RIA). Prophylactic treatment with Co-trimoxazole relieved pulmonary infections but failure to thrive remained unchanged in spite of a continuous nutritional support. A vertical mode of transmission of AIDS from mother to child seems very probable.
Keywords: Acquired Immunodeficiency Syndrome/COMPLICATIONS/*TRANSMISSION Case Report Child, Preschool English Abstract Failure to Thrive/ETIOLOGY Female Human Leukoencephalopathy, Progressive Multifocal/ETIOLOGY Pneumonia, Pneumocystis carinii/ETIOLOGY Prognosis Respiratory Tract Infections/ETIOLOGY Thoracic Radiography JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/complications/
860430
M8640158

Copyright © 1986 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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