Steroid-related development of Kaposi's sarcoma in a homosexual man with Burkitt's lymphoma. NLM AIDSLINE Important note: Information in this article was accurate in 1986. The state of the art may have changed since the publication date.

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Steroid-related development of Kaposi's sarcoma in a homosexual man with Burkitt's lymphoma.

Am J Med. 1986 Jan;80(1):119-22. Unique Identifier : AIDSLINE MED/86100520
Real FX; Krown SE; Koziner B

Abstract: The development of Kaposi's sarcoma has been associated with either iatrogenic or disease-related immunodeficiency. This report describes a homosexual man who presented with Burkitt's lymphoma and later had pneumonitis, which was treated with a high dose of corticosteroids. Kaposi's sarcoma subsequently developed, and regressed completely when the chemotherapy and corticosteroid therapy were withdrawn. The evidence from the literature relating corticosteroid therapy to the development of Kaposi's sarcoma is discussed, as well as the possible multifactorial origin of the immunodeficiency in which setting this tumor occurs. The observations in this patient suggest that corticosteroids should be used with extreme caution in patients with acquired immunodeficiency and those at risk for its development.
Keywords: Acquired Immunodeficiency Syndrome/IMMUNOLOGY Adult Antineoplastic Agents, Combined/*THERAPEUTIC USE Burkitt's Lymphoma/*COMPLICATIONS/DRUG THERAPY Case Report *Homosexuality Human Male Pneumonia/DRUG THERAPY Prednisone/*ADVERSE EFFECTS/THERAPEUTIC USE Risk Sarcoma, Kaposi's/*CHEMICALLY INDUCED/IMMUNOLOGY Support, Non-U.S. Gov't Support, U.S. Gov't, P.H.S. JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/immunologyadultantineoplasticagents,combined/KWDtherapeuticuseburkitt'slymphoma/KWDcomplications/drugtherapycasereportKWDhomosexualityhumanmalepneumonia/drugtherapyprednisone/KWDadverseeffects/therapeuticuserisksarcoma,kaposi's/KWDchemicallyinduced/immunologysupport,non-uKWDsKWDgov'tsupport,uKWDsKWDgov't,pKWDhKWDsKWDjournalarticle
860430
M8640124

Copyright © 1986 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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