Lymphocytic interstitial pneumonia associated with the acquired immune deficiency syndrome. NLM AIDSLINE Important note: Information in this article was accurate in 1985. The state of the art may have changed since the publication date.

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Lymphocytic interstitial pneumonia associated with the acquired immune deficiency syndrome.

Am Rev Respir Dis. 1985 Jun;131(6):952-5. Unique Identifier : AIDSLINE MED/85223438
Grieco MH; Chinoy-Acharya P

Abstract: Lymphocytic interstitial pneumonitis (LIP) is characterized by interstitial accumulation of mature lymphocytes, plasma cells, and reticuloendothelial cells and is often an unremitting process unresponsive to immunosuppressive therapy. The patient described in this report had severe candidal esophagitis and immunologic findings consistent with the acquired immune deficiency syndrome (AIDS). There was no evidence of pulmonary infection with Pneumocystis carinii, cytomegalovirus, Mycobacterium avium-intracellulare, or Cryptococcus neoformans. Open lung biopsy revealed multiple discrete nodular foci of inflammation and alveolar inflammation. The inflammatory cells were largely lymphocytes and histiocytes. Thus, LIP may be an infrequent complication of AIDS. Epstein-Barr virus and Chlamydia trachomatis are potential etiologic agents, but a specific cause remains to be identified. This disorder has been described with a higher frequency in pediatric AIDS.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS Adult Biopsy Case Report Histiocytes/PATHOLOGY Human Lymphocytes/PATHOLOGY Male Pulmonary Fibrosis/*COMPLICATIONS/IMMUNOLOGY/PATHOLOGY/ RADIOGRAPHY Thoracic Radiography JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDcomplicationsadultbiopsycasereporthistiocytes/pathologyhumanlymphocytes/pathologymalepulmonaryfibrosis/KWDcomplications/immunology/pathology/radiographythoracicradiographyjournalarticle
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Copyright © 1985 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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