[Biologic individuality between genetics and environment. On the formation of the biologic ego] NLM AIDSLINE Important note: Information in this article was accurate in 1985. The state of the art may have changed since the publication date.

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[Biologic individuality between genetics and environment. On the formation of the biologic ego]

Monatsschr Kinderheilkd. 1985 Apr;133(4):201-6. Unique Identifier : AIDSLINE MED/85213525
Burgio GR

Abstract: Histocompatibility antigens represent the biological basis of individuality. They make men different from one another and represent the essence of self which is continuously protected from non self by the immune system. Both fecundation and the evolution of pregnancy are favoured by a marked difference in histocompatibility antigens of the mother and father as well as of the mother and the fetus. The biology of pregnancy also find expression in the neonate: different percentages of the subclasses of T lymphocytes and low levels of NK cells and function. On the whole these data and the correlation between histocompatibility antigens and diseases allow life to be interpreted as an immune phenomenon and human individuality as an essentially immunological biological Ego. Analogies may be found between the biological and the psychological Ego. Many alterations may affect the protective immune network giving rise to primary or acquired immunodeficiencies. They may be expressed slowly and progressively or suddenly. The immune alterations of Down's syndrome and those of infantile AIDS may be taken as heuristic examples in this sense.
Keywords: Acquired Immunodeficiency Syndrome/GENETICS Child Down Syndrome/GENETICS English Abstract Female Human HLA Antigens/GENETICS Immunity, Cellular *Immunocompetence Immunologic Deficiency Syndromes/*GENETICS/IMMUNOLOGY Infant, Newborn Maternal-Fetal Exchange Phenotype Pregnancy Risk JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/geneticschilddownsyndrome/geneticsenglishabstractfemalehumanhlaantigens/geneticsimmunity,cellularKWDimmunocompetenceimmunologicdeficiencysyndromes/KWDgenetics/immunologyinfant,newbornmaternal-fetalexchangephenotypepregnancyriskjournalarticle
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M8590082

Copyright © 1985 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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