[Hepatic involvement in the acquired immunodeficiency syndrome. Study of 20 cases] NLM AIDSLINE Important note: Information in this article was accurate in 1985. The state of the art may have changed since the publication date.

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[Hepatic involvement in the acquired immunodeficiency syndrome. Study of 20 cases]

Presse Med. 1985 May 25;14(21):1177-80. Unique Identifier : AIDSLINE MED/85216339
Devars du Mayne JF; Marche C; Penalba C; Vittecoq D; Saimot G; Cerf M

Abstract: Liver biopsies were systematically performed in 20 patients with evidence of an acquired immunodeficiency syndrome (18 with opportunistic infections, 9 with Kaposi's sarcoma). Hepatitis, related to hepatitis-B virus in 3 cases and to cytomegalovirus in 3 cases, was present in 6 of them. All patients had at least one of the three following lesions: non-specific portal inflammatory infiltration (6 cases), granulomatous lesions (12 cases), vascular abnormalities (12 cases). Among hepatic granulomatous lesions: 3 were due to acid-fast bacilli and 1 to Cryptococcus. Sinusoidal abnormality included proliferation of Kupffer cells (9 cases), sinusoidal dilatation (2 cases), peliosis (4 cases) and Kaposi's sarcoma (1 case). A relationship between these abnormalities cannot be excluded.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS/PATHOLOGY Adult Bacterial Infections/MICROBIOLOGY English Abstract Female Hepatitis/MICROBIOLOGY Hepatitis Viruses/ISOLATION & PURIF Hepatitis, Viral, Human/ETIOLOGY Human Liver/BLOOD SUPPLY/MICROBIOLOGY/*PATHOLOGY Liver Diseases/*ETIOLOGY/PATHOLOGY Male Mycoses/MICROBIOLOGY JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDcomplications/pathologyadultbacterialinfections/microbiologyenglishabstractfemalehepatitis/microbiologyhepatitisviruses/isolation&purifhepatitis,viral,human/etiologyhumanliver/bloodsupply/microbiology/KWDpathologyliverdiseases/KWDetiology/pathologymalemycoses/microbiologyjournalarticle
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M8590079

Copyright © 1985 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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