Mechanisms of virus-induced immune suppression. NLM AIDSLINE Important note: Information in this article was accurate in 1985. The state of the art may have changed since the publication date.

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Mechanisms of virus-induced immune suppression.

Can Med Assoc J. 1985 Jun 1;132(11):1261-7. Unique Identifier : AIDSLINE MED/85201280
Wainberg MA; Mills EL

Abstract: The recent demonstration that the acquired immune deficiency syndrome (AIDS) is caused by a retrovirus that affects humans has given rise to widespread concern about the immunosuppressive properties of viruses in general. A wide variety of viruses have been shown to be able to compromise immune function. Sometimes immunosuppression results from the pathologic processes that viruses are able to induce. In other instances virus-induced immune derangements may themselves be responsible for the onset of pathologic change. In some cases a single infectious viral agent may be able to modulate several immunologic mechanisms simultaneously. This review discusses some of the various complex mechanisms through which viral infections can alter the function of the immune system.
Keywords: Acquired Immunodeficiency Syndrome/IMMUNOLOGY/MICROBIOLOGY Burkitt's Lymphoma/IMMUNOLOGY Cell Transformation, Viral Cytomegalovirus Infections/IMMUNOLOGY Herpesvirus 4, Human/IMMUNOLOGY Human Immunity, Cellular *Immunosuppression Interleukin-2/*IMMUNOLOGY Killer Cells/IMMUNOLOGY/MICROBIOLOGY Support, Non-U.S. Gov't T-Lymphocytes/IMMUNOLOGY/*MICROBIOLOGY Virus Diseases/*IMMUNOLOGY Viruses/IMMUNOLOGY JOURNAL ARTICLE REVIEW

KWDacquiredimmunodeficiencysyndrome/immunology/microbiologyburkitt'slymphoma/immunologycelltransformation,viralcytomegalovirusinfections/immunologyherpesvirus4,human/immunologyhumanimmunity,cellularKWDimmunosuppressioninterleukin-2/KWDimmunologykillercells/immunology/microbiologysupport,non-uKWDsKWDgov'tt-lymphocytes/immunology/KWDmicrobiologyvirusdiseases/KWDimmunologyviruses/immunologyjournalarticlereview
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M8590069

Copyright © 1985 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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