Gastrointestinal Kaposi's sarcoma in patients with acquired immunodeficiency syndrome. Endoscopic and autopsy findings. NLM AIDSLINE Important note: Information in this article was accurate in 1985. The state of the art may have changed since the publication date.

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Gastrointestinal Kaposi's sarcoma in patients with acquired immunodeficiency syndrome. Endoscopic and autopsy findings.

Gastroenterology. 1985 Jul;89(1):102-8. Unique Identifier : AIDSLINE MED/85231841
Friedman SL; Wright TL; Altman DF

Abstract: Homosexual men with acquired immunodeficiency syndrome and Kaposi's sarcoma (KS) have been studied to define the extent of gastrointestinal KS. In 50 patients examined by both upper endoscopy and flexible fiberoptic sigmoidoscopy, 20 (40%) had visible lesions consistent with KS. Ten patients (20%) had upper and lower tract involvement, 6 (12%) patients had upper tract involvement alone, and 4 (8%) had lower tract disease alone. Only 23% of endoscopic biopsies of KS lesions were positive for KS. Gastrointestinal KS was not more frequent in patients with nodal KS (41%) than in patients with skin KS (50%). No clinical sequelae of gastrointestinal KS lesions were seen. Mortality was significantly greater in those patients with endoscopic evidence of gastrointestinal KS. Postmortem examination of 13 men with KS and acquired immunodeficiency syndrome revealed abdominal visceral involvement in 10 patients (77%). Antemortem endoscopic findings correlated with subsequent autopsy data in 5 patients. Our findings suggest that visceral involvement, though rarely symptomatic, may be associated with a poorer prognosis.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS Adult Autopsy Endoscopy Gastrointestinal Neoplasms/*PATHOLOGY Human Liver/PATHOLOGY Male Prognosis Sarcoma, Kaposi's/ETIOLOGY/MORTALITY/*PATHOLOGY Sigmoid/PATHOLOGY Support, U.S. Gov't, P.H.S. JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDcomplicationsadultautopsyendoscopygastrointestinalneoplasms/KWDpathologyhumanliver/pathologymaleprognosissarcoma,kaposi's/etiology/mortality/KWDpathologysigmoid/pathologysupport,uKWDsKWDgov't,pKWDhKWDsKWDjournalarticle
851030
M85A0158

Copyright © 1985 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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