Paraproteinemia in patients with acquired immunodeficiency syndrome (AIDS) or lymphadenopathy syndrome (LAS). NLM AIDSLINE Important note: Information in this article was accurate in 1985. The state of the art may have changed since the publication date.

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Paraproteinemia in patients with acquired immunodeficiency syndrome (AIDS) or lymphadenopathy syndrome (LAS).

Clin Chem. 1985 Jul;31(7):1224-6. Unique Identifier : AIDSLINE MED/85228782
Heriot K; Hallquist AE; Tomar RH


Abstract: Eight of 15 patients with acquired immunodeficiency syndrome (AIDS) and six of nine patients with lymphadenopathy syndrome (LAS) had paraproteins in their sera. Twelve of these 14 were IgG kappa; the other two had no demonstrable light chains. The relationship of the paraprotein to the pathogenesis of AIDS is not clear, but we discuss its relation to derangements of B-cell immune regulation and function and to B-cell tumors in AIDS patients.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS Human IgG/ANALYSIS Immunoelectrophoresis Immunoglobulins, kappa-Chain/ANALYSIS Lymphatic Diseases/*COMPLICATIONS Male Paraproteinemias/*COMPLICATIONS JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDcomplicationshumanigg/analysisimmunoelectrophoresisimmunoglobulins,kappa-chain/analysislymphaticdiseases/KWDcomplicationsmaleparaproteinemias/KWDcomplicationsjournalarticle
851030
M85A0106


Copyright © 1985 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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