Sera of adult T-cell leukemia patients and carriers of human T-cell leukemia virus type I in Japan do not cross-react with antigens of lymphadenopathy virus. NLM AIDSLINE Important note: Information in this article was accurate in 1985. The state of the art may have changed since the publication date.

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Sera of adult T-cell leukemia patients and carriers of human T-cell leukemia virus type I in Japan do not cross-react with antigens of lymphadenopathy virus.

Jpn J Cancer Res. 1985 Apr;76(4):245-8. Unique Identifier : AIDSLINE MED/85231773
Katamine S; Sugiyama H; Moriuchi R; Miyamoto T; Hino S

Abstract: The immunological cross-reactivity of human T-cell leukemia virus type I (HTLV-I)-related sera with lymphadenopathy virus (LAV) was investigated. The sera tested were obtained from 36 adult T-cell leukemia patients, 182 HTLV-I carriers, and 284 control individuals in Nagasaki. Two test methods were utilized: indirect immunofluorescence on LAV-producing cells and solid-phase radioimmunoassay with lysate of LAV. The results were exclusively negative for the presence of antibody activity against LAV, indicating the absence of cross-reaction and endemy in Nagasaki.
Keywords: Antigens, Viral/*IMMUNOLOGY Carrier State/*IMMUNOLOGY Cross Reactions Fluorescent Antibody Technique Human HTLV-BLV Viruses/*IMMUNOLOGY Leukemia/*IMMUNOLOGY Radioimmunoassay Retroviridae Infections/*IMMUNOLOGY Support, Non-U.S. Gov't T-Lymphocytes JOURNAL ARTICLE

KWDantigens,viral/KWDimmunologycarrierstate/KWDimmunologycrossreactionsfluorescentantibodytechniquehumanhtlv-blvviruses/KWDimmunologyleukemia/KWDimmunologyradioimmunoassayretroviridaeinfections/KWDimmunologysupport,non-uKWDsKWDgov'tt-lymphocytesjournalarticle
851030
M85A0073

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