The histomorphology of Kaposi sarcoma in three homosexual men. NLM AIDSLINE Important note: Information in this article was accurate in 1985. The state of the art may have changed since the publication date.

Click here to return to AIDSLINE main menu
DonateNow
Print this Article


The histomorphology of Kaposi sarcoma in three homosexual men.

Acta Pathol Microbiol Immunol Scand [A]. 1985 Jan;93(1):17-23. Unique Identifier : AIDSLINE MED/85118351
Thomsen HK; Jacobsen M; Gerstoft J; Malchow-Moller A

Abstract: Three homosexual men with acquired immunodeficiency syndrome (AIDS) were referred to Hvidovre Hospital, Copenhagen, during 1981. Biopsies from lymph nodes (case 2), skin (case 1 and 3), oral mucosal membrane (case 1) and lung (case 3) revealed Kaposi Sarcoma (KS). Furthermore, KS was found at autopsy in several other organs in case 3. While the tumor morphology of the lymph nodes, the oral mucosal membrane, and the internal organs was identical to that of classical KS, the skin lesions appeared different. Macroscopically, the skin lesions in case 1 and 3 were alike, but microscopically, the lesions in the two cases differed from each other. In both cases small tumor infiltrates were dispersed in the dermis with interjacent preserved dermal tissue. In case 1 the tumor infiltrates were composed of different vascular structures including irregular slits formed by dermal collagen fibres lined with long slim tumor cells. In case 2 the infiltrates were mainly composed of solid collections of pale tumor cells with faintly stained nuclei. The difficulties in establishing a diagnosis of KS on skin biopsies from patients with AIDS are emphasized.
Keywords: Acquired Immunodeficiency Syndrome/EPIDEMIOLOGY/PATHOLOGY Adult Case Report Denmark Diagnosis, Differential *Homosexuality Human Lung Neoplasms/PATHOLOGY Lymphatic Metastasis Male Middle Age Mouth Mucosa/PATHOLOGY Mouth Neoplasms/PATHOLOGY Sarcoma, Kaposi's/*PATHOLOGY Skin Neoplasms/PATHOLOGY JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/epidemiology/pathologyadultcasereportdenmarkdiagnosis,differentialKWDhomosexualityhumanlungneoplasms/pathologylymphaticmetastasismalemiddleagemouthmucosa/pathologymouthneoplasms/pathologysarcoma,kaposi's/KWDpathologyskinneoplasms/pathologyjournalarticle
850530
M8550071

Copyright © 1985 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1985. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1985. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .