Enteric coccidiosis among patients with the acquired immunodeficiency syndrome. NLM AIDSLINE Important note: Information in this article was accurate in 1985. The state of the art may have changed since the publication date.

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Enteric coccidiosis among patients with the acquired immunodeficiency syndrome.

Am J Trop Med Hyg. 1984 Nov;33(6):1065-72. Unique Identifier : AIDSLINE MED/85069985
Whiteside ME; Barkin JS; May RG; Weiss SD; Fischl MA; MacLeod CL

Abstract: Ten patients were identified at Jackson Memorial hospital/University of Miami Hospitals and Clinics with enteric coccidial infection due to Cryptosporidium spp. or Isospora belli. All had the acquired immunodeficiency syndrome as manifested by Kaposi's sarcoma or multiple opportunistic infections, or both. They presented with profuse diarrhea associated with weakness, anorexia, and weight loss. Routine examinations of stools for eggs and parasites as performed by the hospital laboratory were negative in all patients. Sugar flotation and modified acid fast techniques were used in the Tropical Disease Laboratory to identify oocysts of Cryptosporidium spp. in stools of seven patients. Malabsorption, characterized by a low 5-hour D-xylose and positive fecal fat, was observed in 6/6 of these patients. In three other patients Isospora belli oocysts were identified in stool specimens or via a duodenal string test. Spiramycin was the only drug found to be effective in treating patients with cryptosporidiosis. Patients with Isospora belli responded to a prolonged course of trimethoprim-sulfamethoxazole.
Keywords: Acquired Immunodeficiency Syndrome/COMPLICATIONS/*PARASITOLOGY Adult Animal Coccidiosis/*COMPLICATIONS/DIAGNOSIS/DRUG THERAPY Cryptosporidiosis/COMPLICATIONS Cryptosporidium Diarrhea/PARASITOLOGY Drug Combinations/THERAPEUTIC USE Female Furazolidone/THERAPEUTIC USE Human Intestinal Diseases, Parasitic/*COMPLICATIONS Isospora Leucomycins/THERAPEUTIC USE Male Middle Age Sulfamethoxazole/THERAPEUTIC USE Trimethoprim/THERAPEUTIC USE JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/complications/KWDparasitologyadultanimalcoccidiosis/KWDcomplications/diagnosis/drugtherapycryptosporidiosis/complicationscryptosporidiumdiarrhea/parasitologydrugcombinations/therapeuticusefemalefurazolidone/therapeuticusehumanintestinaldiseases,parasitic/KWDcomplicationsisosporaleucomycins/therapeuticusemalemiddleagesulfamethoxazole/therapeuticusetrimethoprim/therapeuticusejournalarticle
850330
M8530107

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