[Immunological study of a population of hemophiliacs treated with non-commercial fractions] NLM AIDSLINE Important note: Information in this article was accurate in 1985. The state of the art may have changed since the publication date.

Click here to return to AIDSLINE main menu
DonateNow
Print this Article


[Immunological study of a population of hemophiliacs treated with non-commercial fractions]

Rev Fr Transfus Immunohematol. 1984 Sep;27(4):463-72. Unique Identifier : AIDSLINE MED/85065377
Huart JJ; Boulanger P; Parquet A; Goudemand M

Abstract: We studied lymphocyte subpopulations, serum beta 2 microglobulin, and viral markers in 115 hemophiliacs who are followed and treated at our center. The only clinical or biological anomaly observed is hypergammaglobulinemia. This frequent finding is independent of hemophilia type and of the intensity of substitutive treatment. This group is characterized by the fact that the patients are treated only by locally prepared coagulation fractions, essentially cryoprecipitates for hemophiliacs A, and not containing any derivative of commercial origin. This series is compared to other recent reports, some of which present a high incidence of immunologic anomalies.
Keywords: beta 2-Microglobulin/ANALYSIS Acquired Immunodeficiency Syndrome/ETIOLOGY Blood Transfusion/ADVERSE EFFECTS English Abstract Hemophilia/COMPLICATIONS/*IMMUNOLOGY/MICROBIOLOGY/THERAPY Human Hypergammaglobulinemia/COMPLICATIONS Lymphocytes/ANALYSIS JOURNAL ARTICLE

KWDbeta2-microglobulin/analysisacquiredimmunodeficiencysyndrome/etiologybloodtransfusion/adverseeffectsenglishabstracthemophilia/complications/KWDimmunology/microbiology/therapyhumanhypergammaglobulinemia/complicationslymphocytes/analysisjournalarticle
850330
M8530099

Copyright © 1985 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1985. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1985. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .