Major medical problems and detoxification treatment of parenteral drug-abusing alcoholics.

Important note: Information in this article was accurate in 1985. The state of the art may have changed since the publication date.

Major medical problems and detoxification treatment of parenteral drug-abusing alcoholics.

Adv Alcohol Subst Abuse. 1984 Summer;3(4):87-105. Unique Identifier : AIDSLINE MED/85068981
Novick DM

Abstract: Patients with combined addictive disease are frequently encountered in New York City. Three detoxification schedules have been developed which, alone or in combination, may be used for almost all substance abusers who require pharmacologic detoxification. Numerous factors contribute to pathogenesis of infections in parenteral drug-abusing alcoholics, including aspiration, impaired pulmonary function, immunologic abnormalities, and changes in endogenous microbial flora. The acquired immunodeficiency syndrome (AIDS) has recently emerged as a serious medical complication of parenteral substance abuse. Liver disease in parenteral drug-abusing alcoholics is also multifactorial. The direct hepatotoxic effects of alcohol, the adulterants of illicit, injectable drugs, and infections with the hepatitis B virus, non-A, non-B viruses, and the delta agent may all be contributing factors.

Keywords: Acquired Immunodeficiency Syndrome/ETIOLOGY Alcoholism/COMPLICATIONS/*THERAPY Homosexuality Human Hypnotics and Sedatives/THERAPEUTIC USE Infection/ETIOLOGY Injections, Intravenous Liver Diseases, Alcoholic/ETIOLOGY Male Methadone/ADMINISTRATION & DOSAGE Methicillin/PHARMACOLOGY Narcotic Dependence/THERAPY Penicillin Resistance Phenobarbital/ADMINISTRATION & DOSAGE/THERAPEUTIC USE Staphylococcus aureus/DRUG EFFECTS Substance Abuse/COMPLICATIONS/*THERAPY Substance Withdrawal Syndrome/DRUG THERAPY JOURNAL ARTICLE REVIEW

850330
M8530096

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