[Acquired immunodeficiency syndrome and related syndromes in hemophiliacs: status throughout the world] NLM AIDSLINE Important note: Information in this article was accurate in 1985. The state of the art may have changed since the publication date.

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[Acquired immunodeficiency syndrome and related syndromes in hemophiliacs: status throughout the world]

Rev Fr Transfus Immunohematol. 1984 Sep;27(4):493-6. Unique Identifier : AIDSLINE MED/85065381
Laurian Y; Lambert T; Larrieu MJ

Abstract: The occurrence during the last 2 years of 29 cases of AIDS in hemophiliacs (21 in USA and 8 in Europe) suggests possible transmission of this disease by blood products. All these patients had received Factor VIII or IX concentrates and developed pneumocystis carinii pneumonia or other opportunistic infections. Kaposi's sarcoma was not observed in any patient. Recent studies have focused on the frequency of AIDS-related complex in hemophiliacs, which may arise as a crucial problem. However this does not justify at the moment any reduction in the substitutive treatment of hemophiliac patients unless new clues to the understanding of these disorders are provided. Therefore, it is mostly important to clearly define, through research programs and precise follow-up of patients, blood products which can be used safely in hemophiliacs.
Keywords: Acquired Immunodeficiency Syndrome/*EPIDEMIOLOGY Blood Transfusion/ADVERSE EFFECTS English Abstract Epidemiologic Methods Europe Factor IX/THERAPEUTIC USE Factor VIII/THERAPEUTIC USE Hemophilia/*COMPLICATIONS/THERAPY Human United States JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDepidemiologybloodtransfusion/adverseeffectsenglishabstractepidemiologicmethodseuropefactorix/therapeuticusefactorviii/therapeuticusehemophilia/KWDcomplications/therapyhumanunitedstatesjournalarticle
850330
M8530090

Copyright © 1985 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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