[A new HTLV retrovirus associated with human T-cell leukemia/lymphoma] NLM AIDSLINE Important note: Information in this article was accurate in 1985. The state of the art may have changed since the publication date.

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[A new HTLV retrovirus associated with human T-cell leukemia/lymphoma]

Eksp Onkol. 1984;6(3):3-9. Unique Identifier : AIDSLINE MED/85050927
Kiselev FL

Abstract: The data concerning retrovirus HTLV isolated from patients with T-cell leukemia/lymphoma are presented. The virus differs from the known C type viruses, possesses high tropism to T-lymphocytes. The virus is exogenous for human cells and its origin is still unknown. Virus specific nucleotide sequences are absent in a normal cell genome, but they are detected in blood cells and tissues of patients with this form of leukemia. HTLV-associated disease is rare and distributed mainly in two regions in the world: in the South-West of Japan and in the Caribbean islands. Mode of the virus transmission is probably horizontal.
Keywords: Animal Antibodies, Monoclonal/DIAGNOSTIC USE Antibodies, Viral/ANALYSIS Antigens, Viral/IMMUNOLOGY Cell Line Cell Transformation, Viral DNA, Viral/GENETICS English Abstract Genes, Viral Human HTLV-BLV Viruses/*GENETICS/IMMUNOLOGY Japan Leukemia/EPIDEMIOLOGY/*ETIOLOGY/GENETICS Lymphoma/EPIDEMIOLOGY/*ETIOLOGY/GENETICS Macaca mulatta Mice Oncogenes Retroviridae Infections/EPIDEMIOLOGY/GENETICS/*MICROBIOLOGY T-Lymphocytes/MICROBIOLOGY Viral Proteins/ANALYSIS West Indies JOURNAL ARTICLE REVIEW

KWDanimalantibodies,monoclonal/diagnosticuseantibodies,viral/analysisantigens,viral/immunologycelllinecelltransformation,viraldna,viral/geneticsenglishabstractgenes,viralhumanhtlv-blvviruses/KWDgenetics/immunologyjapanleukemia/epidemiology/KWDetiology/geneticslymphoma/epidemiology/KWDetiology/geneticsmacacamulattamiceoncogenesretroviridaeinfections/epidemiology/genetics/KWDmicrobiologyt-lymphocytes/microbiologyviralproteins/analysiswestindiesjournalarticlereview
850330
M8530070

Copyright © 1985 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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