[X-linked lymphoproliferative syndrome] NLM AIDSLINE Important note: Information in this article was accurate in 1985. The state of the art may have changed since the publication date.

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[X-linked lymphoproliferative syndrome]

Tijdschr Kindergeneeskd. 1984 Dec;52(6):244-8. Unique Identifier : AIDSLINE MED/85142987
Weening RS; van Zaane DJ; Sanders MK; Bakker PM

Abstract: This report deals with the case history of a 21/2-year old Turkish boy, who died from an overwhelming mononucleosis infectiosa. The parents, first cousins, lost already two sons and a daughter. According to the parents, the symptoms of these children resembled those of this boy. In the patient, described here, an acquired immunodeficiency was found, probably induced by the Epstein-Barr virus on the basis of a genetic susceptibility for this virus. The family history, the clinical picture, together with the serological, immunological - and histological examinations, pointed to the diagnosis of X-linked recessive lymfoproliferative syndrome (XLP), as described by Purtilo. The immunological findings resemble those of AIDS (acquired immunodeficiency syndrome).
Keywords: Acquired Immunodeficiency Syndrome/COMPLICATIONS Case Report Child, Preschool Consanguinity English Abstract Female Genes, Recessive Human Infectious Mononucleosis/*COMPLICATIONS Linkage (Genetics) Lymphoproliferative Disorders/COMPLICATIONS/*GENETICS Male Pedigree *X Chromosome JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/complicationscasereportchild,preschoolconsanguinityenglishabstractfemalegenes,recessivehumaninfectiousmononucleosis/KWDcomplicationslinkage(genetics)lymphoproliferativedisorders/complications/KWDgeneticsmalepedigreeKWDxchromosomejournalarticle
850630
M8560155

Copyright © 1985 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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