Transfusion-mediated spread of the human T-cell leukemia virus in chronic hemodialysis patients in a heavily endemic area, Nagasaki. NLM AIDSLINE Important note: Information in this article was accurate in 1985. The state of the art may have changed since the publication date.

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Transfusion-mediated spread of the human T-cell leukemia virus in chronic hemodialysis patients in a heavily endemic area, Nagasaki.

Gann. 1984 Dec;75(12):1070-5. Unique Identifier : AIDSLINE MED/85128202
Hino S; Kawamichi T; Funakoshi M; Kanamura M; Kitamura T; Miyamoto T

Abstract: The incidence of anti-adult T-cell leukemia-associated antigens (ATLA) was surveyed in 134 patients under chronic hemodialysis in the Nagasaki area, as well as 4708 blood donors resident in the same area as controls: 23 patients (17%) and 201 donors (4.3%) were positive for anti-ATLA antibody. All seropositive patients were found to have had a positive history of blood transfusions. Seroconversions were confirmed in 9 cases, all of them after initiation of transfusions. In total, 216 units of blood were transfused in 7 seroconverted patients, and this is consistent with the estimated rate of anti-ATLA antibody-positive donor blood supplied by the Red Cross Nagasaki Blood Center (5%).
Keywords: Adult Aged Antibodies, Viral/ANALYSIS Blood Transfusion/*ADVERSE EFFECTS Female *Hemodialysis Human *HTLV-BLV Viruses/IMMUNOLOGY Japan Leukemia/*TRANSMISSION Male Middle Age Retroviridae Infections/*TRANSMISSION JOURNAL ARTICLE

KWDadultagedantibodies,viral/analysisbloodtransfusion/KWDadverseeffectsfemaleKWDhemodialysishumanKWDhtlv-blvviruses/immunologyjapanleukemia/KWDtransmissionmalemiddleageretroviridaeinfections/KWDtransmissionjournalarticle
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M8560143

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