Intracranial space-occupying lesions in acquired immune deficiency syndrome patients. NLM AIDSLINE Important note: Information in this article was accurate in 1985. The state of the art may have changed since the publication date.

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Intracranial space-occupying lesions in acquired immune deficiency syndrome patients.

Neurosurgery. 1985 Feb;16(2):148-53. Unique Identifier : AIDSLINE MED/85138317
Snow RB; Lavyne MH

Abstract: The recent description of the acquired immune deficiency syndrome (AIDS) followed the observation of an increased incidence of unusual neoplasms and opportunistic infections in previously healthy homosexual men, intravenous drug abusers, Haitians, hemophiliacs, and certain infants. Active research efforts on this group of patients established a defect in cellular immunity. Six patients with AIDS who underwent neurosurgical procedures for intracranial space-occupying lesions are presented. Two of the patients had toxoplasmosis brain abscesses, one had primary central nervous system lymphoma, one had cytomegalovirus encephalitis, one had progressive multifocal leukoencephalopathy, and one patient remained undiagnosed despite pathological examination of the brain tissue specimen. We recommend brain biopsy in AIDS patients with space-occupying lesions because the regimen for the various conditions differs. Although the central nervous system diseases found in AIDS patients are associated with a high mortality rate, four of the six patients responded favorably to specific treatment.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS Adult Brain Abscess/COMPLICATIONS Brain Diseases/*COMPLICATIONS Brain Neoplasms/COMPLICATIONS Human Leukoencephalopathy, Progressive Multifocal/COMPLICATIONS Lymphoma/COMPLICATIONS Male Toxoplasmosis/COMPLICATIONS JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDcomplicationsadultbrainabscess/complicationsbraindiseases/KWDcomplicationsbrainneoplasms/complicationshumanleukoencephalopathy,progressivemultifocal/complicationslymphoma/complicationsmaletoxoplasmosis/complicationsjournalarticle
850630
M8560109

Copyright © 1985 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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