Toxoplasmosis presenting as panhypopituitarism in a patient with the acquired immune deficiency syndrome. NLM AIDSLINE Important note: Information in this article was accurate in 1985. The state of the art may have changed since the publication date.

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Toxoplasmosis presenting as panhypopituitarism in a patient with the acquired immune deficiency syndrome.

Am J Med. 1984 Oct;77(4):760-4. Unique Identifier : AIDSLINE MED/85020139
Milligan SA; Katz MS; Craven PC; Strandberg DA; Russell IJ; Becker RA

Abstract: A 57-year-old man with a prior episode of lymphatic toxoplasmosis presented with signs of anterior panhypopituitarism, which was confirmed by standard endocrinologic evaluation. The diagnosis of central nervous system toxoplasmosis was established by brain biopsy after nondiagnostic serologic and radiographic studies. At autopsy, the anterior pituitary was necrotic, with Toxoplasma abscesses in neighboring brain structures. Clinical and laboratory data met the criteria for the acquired immune deficiency syndrome. Although this is the first reported case of toxoplasmosis presenting as panhypopituitarism, future cases may be identified since central nervous system toxoplasmosis is being recognized more frequently in patients with immunodeficiency.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS Brain Diseases/COMPLICATIONS/*PARASITOLOGY Case Report Cerebral Angiography Diagnosis, Differential Hormones/BLOOD Human Hypopituitarism/*ETIOLOGY/RADIOGRAPHY IgG/ANALYSIS Male Middle Age Tomography, X-Ray Computed Toxoplasma/IMMUNOLOGY Toxoplasmosis/*COMPLICATIONS/IMMUNOLOGY JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDcomplicationsbraindiseases/complications/KWDparasitologycasereportcerebralangiographydiagnosis,differentialhormones/bloodhumanhypopituitarism/KWDetiology/radiographyigg/analysismalemiddleagetomography,x-raycomputedtoxoplasma/immunologytoxoplasmosis/KWDcomplications/immunologyjournalarticle
850130
M8510068

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