Adult T-cell leukemia-lymphoma with mediastinal involvement and an asymptomatic chronic phase. NLM AIDSLINE Important note: Information in this article was accurate in 1985. The state of the art may have changed since the publication date.

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Adult T-cell leukemia-lymphoma with mediastinal involvement and an asymptomatic chronic phase.

Can Med Assoc J. 1984 Sep 15;131(6):595-600. Unique Identifier : AIDSLINE MED/85001668
Amato D; Fernandes BJ; Klein M

Abstract: A black, West Indian woman with adult T-cell leukemia-lymphoma (ATLL), hypercalcemia, peripheral and retroperitoneal lymphadenopathy, and serum antibodies to human T-lymphotropic virus (HTLV) was found to have massive mediastinal adenopathy, a feature not previously reported in patients with ATLL. In addition, she had had asymptomatic leukocytosis with marked lymphocytosis for at least 6 years before presenting with full-blown ATLL. These findings broaden the clinical picture of ATLL. Cell surface-marker studies and close follow-up are recommended for patients with apparent chronic lymphocytic leukemia, especially if they have pleomorphic lymphocytosis, are younger than usual or are from the Caribbean or Japan.
Keywords: Adult Case Report Female Human Hypercalcemia/COMPLICATIONS HTLV-BLV Viruses/IMMUNOLOGY Jamaica/ETHNOLOGY Leukemia/*COMPLICATIONS/PATHOLOGY Lymphatic Diseases/*COMPLICATIONS/PATHOLOGY Lymphocytosis/COMPLICATIONS Lymphoma/*COMPLICATIONS/PATHOLOGY Mediastinal Diseases/*COMPLICATIONS/PATHOLOGY T-Lymphocytes JOURNAL ARTICLE

KWDadultcasereportfemalehumanhypercalcemia/complicationshtlv-blvviruses/immunologyjamaica/ethnologyleukemia/KWDcomplications/pathologylymphaticdiseases/KWDcomplications/pathologylymphocytosis/complicationslymphoma/KWDcomplications/pathologymediastinaldiseases/KWDcomplications/pathologyt-lymphocytesjournalarticle
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