T lymphocyte subsets in homosexual men from Copenhagen. NLM AIDSLINE Important note: Information in this article was accurate in 1985. The state of the art may have changed since the publication date.

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T lymphocyte subsets in homosexual men from Copenhagen.

Eur J Clin Invest. 1984 Aug;14(4):301-5. Unique Identifier : AIDSLINE MED/85003767
Gerstoft J; Petersen CS; Kroon S; Ullman S; Bentsen K; Dickmeiss E; Nielsen JO; Mogens H; Andersen K; Lorenzen I


Abstract: Screening of sixty-six asymptomatic homosexual men from Copenhagen revealed significantly lower Leu-3a/Leu-2a ratios as compared to controls. Ten (15%) of the homosexuals had a ratio less than or equal to 1.0. The low Leu-3a/Leu-2a ratios were the result of an increase in the absolute number of Leu-2a cells. Homosexuals with many partners and those who had been sexual partners of patients with the acquired immuno-deficiency syndrome (AIDS) had significantly lower ratios than those without these features. Cytomegalovirus was isolated from urine and/or sputum of 15% and this was associated with a Leu-3a/Leu-2a ratio less than or equal to 1.0. The observed immunological abnormalities could either represent latent infection with the putative AIDS agent or alternatively be caused by repeated infections and/or exposure to allogenic spermatocytes or lymphocytes.
Keywords: Acquired Immunodeficiency Syndrome/IMMUNOLOGY/TRANSMISSION Antibodies, Viral/ANALYSIS Cytomegalovirus/IMMUNOLOGY/ISOLATION & PURIF Denmark Gonorrhea/IMMUNOLOGY *Homosexuality Human Male Syphilis/IMMUNOLOGY T-Lymphocytes/*IMMUNOLOGY JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/immunology/transmissionantibodies,viral/analysiscytomegalovirus/immunology/isolation&purifdenmarkgonorrhea/immunologyKWDhomosexualityhumanmalesyphilis/immunologyt-lymphocytes/KWDimmunologyjournalarticle
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