Open lung biopsy in immunocompromised patients. NLM AIDSLINE Important note: Information in this article was accurate in 1985. The state of the art may have changed since the publication date.

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Open lung biopsy in immunocompromised patients.

Chest. 1984 Nov;86(5):671-4. Unique Identifier : AIDSLINE MED/85026336
McKenna RJ Jr; Mountain CF; McMurtrey MJ

Abstract: Increased use of open lung biopsy in the search for a treatable etiology of acute interstitial pneumonitis (AIP) in immunocompromised patients is based on the assumption that examination and cultures from biopsy specimens will yield significant information leading to beneficial treatment of the condition. To assess the true impact of the results of open lung biopsy on the subsequent treatment and outcome in such patients, a retrospective study was done of 64 consecutive patients undergoing the procedure in a recent five-year period. When open lung biopsy was performed for the diagnosis of AIP in immunocompromised patients after empiric broad spectrum treatment failed, it rarely missed a specific, treatable etiology, if present. However, the results from open lung biopsy infrequently lead to a change in the treatment that improves the patient's clinical course.
Keywords: Acquired Immunodeficiency Syndrome/COMPLICATIONS Adolescence Adult Aged Biopsy/METHODS Child Female Human Immunosuppression/*ADVERSE EFFECTS Lung/*PATHOLOGY Lung Diseases/*PATHOLOGY Male Middle Age Pulmonary Fibrosis/DRUG THERAPY/ETIOLOGY/PATHOLOGY JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/complicationsadolescenceadultagedbiopsy/methodschildfemalehumanimmunosuppression/KWDadverseeffectslung/KWDpathologylungdiseases/KWDpathologymalemiddleagepulmonaryfibrosis/drugtherapy/etiology/pathologyjournalarticle
850228
M8520121

Copyright © 1985 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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