Microvascular aspects of acquired immune deficiency syndrome retinopathy. NLM AIDSLINE Important note: Information in this article was accurate in 1985. The state of the art may have changed since the publication date.

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Microvascular aspects of acquired immune deficiency syndrome retinopathy.

Am J Ophthalmol. 1984 Nov;98(5):590-601. Unique Identifier : AIDSLINE MED/85044044
Newsome DA; Green WR; Miller ED; Kiessling LA; Morgan B; Jabs DA; Polk BF

Abstract: Twelve of 13 patients with the acquired immune deficiency syndrome exhibited ophthalmoscopically detectable retinal findings, including cotton-wool spots, hemorrhages, Roth spots, and microvascular changes. When we used fluorescein angiography, we detected focal nonperfusion and microvascular changes in all 13 of our patients. Most patients had no visual complaints unless they had cytomegalovirus involvement of the optic papilla or the central retina. One patient lost central visual acuity from loss of perfusion in a portion of his perifoveal capillary net. Histopathologic studies demonstrated the loss of retinal capillary cells and focal occlusions of small vessels. Retinal vessel walls were also thickened with PAS-positive material.
Keywords: Acquired Immunodeficiency Syndrome/COMPLICATIONS/*PATHOLOGY Adult Case Report Eye/*BLOOD SUPPLY Eye Diseases/COMPLICATIONS/*PATHOLOGY Female Fluorescein Angiography Human Male Middle Age Retinal Diseases/COMPLICATIONS/PATHOLOGY Support, U.S. Gov't, P.H.S. JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/complications/KWDpathologyadultcasereporteye/KWDbloodsupplyeyediseases/complications/KWDpathologyfemalefluoresceinangiographyhumanmalemiddleageretinaldiseases/complications/pathologysupport,uKWDsKWDgov't,pKWDhKWDsKWDjournalarticle
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M8520105

Copyright © 1985 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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