Smoldering encephalitis in children. NLM AIDSLINE Important note: Information in this article was accurate in 1985. The state of the art may have changed since the publication date.

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Smoldering encephalitis in children.

Neuropediatrics. 1984 Oct;15(4):191-7. Unique Identifier : AIDSLINE MED/85036884
Gupta PC; Rapin I; Houroupian DS; Roy S; Llena JF; Tandon PN

Abstract: Five children presented with focal seizures and neurological deficits that progressed over a span of months to years. Three had temporal lobectomy to control seizures, one underwent temporal lobe biopsy, and the fifth, who suffered from immunodeficiency, had an occipital lobectomy to remove a mass. Two of the children expired. Neuropathological findings in all five children were consistent with a persistent active viral encephalitis. No infectious agent was identified. None of the children had the usual systemic signs of encephalitis and all lacked an inflammatory response in their cerebrospinal fluid. We conjecture that this condition may be more frequent than realized. Besides causing intractable focal seizures and hemiparesis, it may account for other poorly understood syndromes of childhood with deteriorating behavior.
Keywords: Brain/PATHOLOGY Case Report Child Child, Preschool Chronic Disease Electroencephalography Encephalitis/MICROBIOLOGY/*PATHOLOGY Epilepsy, Partial/*PATHOLOGY Epilepsy, Temporal Lobe/*PATHOLOGY Female Follow-Up Studies Human Immunologic Deficiency Syndromes/PATHOLOGY Infant Male Support, U.S. Gov't, P.H.S. Tomography, X-Ray Computed Virus Diseases/MICROBIOLOGY/PATHOLOGY Viruses/ISOLATION & PURIF JOURNAL ARTICLE

KWDbrain/pathologycasereportchildchild,preschoolchronicdiseaseelectroencephalographyencephalitis/microbiology/KWDpathologyepilepsy,partial/KWDpathologyepilepsy,temporallobe/KWDpathologyfemalefollow-upstudieshumanimmunologicdeficiencysyndromes/pathologyinfantmalesupport,uKWDsKWDgov't,pKWDhKWDsKWDtomography,x-raycomputedvirusdiseases/microbiology/pathologyviruses/isolation&purifjournalarticle
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M8520070

Copyright © 1985 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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