Human T-cell leukemia virus: transformation in vitro of nonhuman primate T-lymphocytes and experimental inoculation of nonhuman primates. NLM AIDSLINE Important note: Information in this article was accurate in 1985. The state of the art may have changed since the publication date.

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Human T-cell leukemia virus: transformation in vitro of nonhuman primate T-lymphocytes and experimental inoculation of nonhuman primates.

Ann N Y Acad Sci. 1984;437:563-7. Unique Identifier : AIDSLINE MED/85197404
Falk LA Jr; Byington R; Silva DP

Abstract: T-lymphocytes from three species of New World monkeys were susceptible to transformation in vitro with human T-cell leukemia virus. Marmoset T-lymphocytes transformed in vitro with HVS or HVA, T-lymphotropic herpesviruses of New World monkeys, were also transformed with HTLV resulting in doubly transformed T-cells. This finding may provide a potential model for investigating the possible interaction between a herpesvirus and T-lymphotropic retroviruses in the clinical condition AIDS.
Keywords: Animal Antigens, Viral Callithrix Cells, Cultured Fluorescent Antibody Technique HTLV-BLV Viruses/*IMMUNOLOGY Lymphocyte Transformation Macaca mulatta Saguinus Saimiri Support, U.S. Gov't, P.H.S. T-Lymphocytes/*IMMUNOLOGY JOURNAL ARTICLE

KWDanimalantigens,viralcallithrixcells,culturedfluorescentantibodytechniquehtlv-blvviruses/KWDimmunologylymphocytetransformationmacacamulattasaguinussaimirisupport,uKWDsKWDgov't,pKWDhKWDsKWDt-lymphocytes/KWDimmunologyjournalarticle
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M8580102

Copyright © 1985 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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