Glomerular lesions in the acquired immunodeficiency syndrome. NLM AIDSLINE Important note: Information in this article was accurate in 1984. The state of the art may have changed since the publication date.

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Glomerular lesions in the acquired immunodeficiency syndrome.

Ann Intern Med. 1984 Oct;101(4):429-34. Unique Identifier : AIDSLINE MED/84305411
Pardo V; Aldana M; Colton RM; Fischl MA; Jaffe D; Moskowitz L; Hensley GT; Bourgoignie JJ

Abstract: Between January 1982 and December 1983, 75 patients with the acquired immunodeficiency syndrome were identified in our hospitals: 35% used intravenous drugs, 50% had proteinuria in excess of 0.5 g/dL, and 10% were nephrotic. Glomerular changes seen at autopsy in 36 patients included frequent mesangial lesions and deposits associated with mild asymptomatic proteinuria. Focal and segmental glomerular sclerosis was found in 5 patients and 4 of these had the nephrotic syndrome. Whereas reversible episodes of acute renal failure were not uncommon, terminal episodes of acute renal insufficiency occurred in 14 patients. The short survival of these patients may prevent the development of chronic renal failure.
Keywords: Acquired Immunodeficiency Syndrome/COMPLICATIONS/IMMUNOLOGY/ *PATHOLOGY Adult Complement 3/ANALYSIS Female Glomerulosclerosis, Focal/ETIOLOGY Human IgM/ANALYSIS Kidney Failure, Acute/ETIOLOGY Kidney Glomerulus/IMMUNOLOGY/*PATHOLOGY Male Middle Age Nephrosis, Lipoid/ETIOLOGY Nephrotic Syndrome/ETIOLOGY Prospective Studies Proteinuria/*ETIOLOGY/PATHOLOGY Support, Non-U.S. Gov't Support, U.S. Gov't, Non-P.H.S. Support, U.S. Gov't, P.H.S. JOURNAL ARTICLE

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841230
M84C0089

Copyright © 1984 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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