Type-I HTLV antibody in urban and rural Ghana, West Africa. NLM AIDSLINE Important note: Information in this article was accurate in 1984. The state of the art may have changed since the publication date.

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Type-I HTLV antibody in urban and rural Ghana, West Africa.

Int J Cancer. 1984 Aug 15;34(2):215-9. Unique Identifier : AIDSLINE MED/84287956
Biggar RJ; Saxinger C; Gardiner C; Collins WE; Levine PH; Clark JW; Nkrumah FK; Blattner WA

Abstract: The prevalence of antibodies against the newly described human T-cell lymphoma virus, type I (HTLV-I) in two communities in Ghana, West Africa, is described. There was no difference by community (urban, 3.6% and rural, 4.0%). Prevalence increased with age, being 5.9% among persons greater than 10 years old, but did not differ by sex. There was no difference when data were analysed by housing status or crowding. Non-confirmed reactions in the assay system were frequent and correlated with both prevalence and titer of antibody against malaria. Possible explanations include vector-borne transmission like that of malaria, but the relationship is more probably due to a polyclonal stimulation of B cells, enhancing the potential for detecting reactivity in the assay. Because assay systems vary and because most laboratories do not routinely use a confirmation assay, results presented by different groups must be interpreted cautiously.
Keywords: Adolescence Adult Age Factors Antibodies/ANALYSIS Antibodies, Viral/*ANALYSIS Child Child, Preschool Comparative Study Female Ghana Herpesvirus 4, Human/IMMUNOLOGY Human HTLV-BLV Viruses/IMMUNOLOGY Infant Male Plasmodium falciparum/IMMUNOLOGY Retroviridae Infections/*IMMUNOLOGY Rural Population Socioeconomic Factors Urban Population JOURNAL ARTICLE

KWDadolescenceadultagefactorsantibodies/analysisantibodies,viral/KWDanalysischildchild,preschoolcomparativestudyfemaleghanaherpesvirus4,human/immunologyhumanhtlv-blvviruses/immunologyinfantmaleplasmodiumfalciparum/immunologyretroviridaeinfections/KWDimmunologyruralpopulationsocioeconomicfactorsurbanpopulationjournalarticle
841230
M84C0037

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