About one-third of all patients with the acquired immunodeficiency syndrome (AIDS) have Kaposi s sarcoma. Gastrointestinal involvement has been noted in 50% of homosexual men with cutaneous Kaposi s sarcoma and AIDS. We report the abnormalities on barium studies of nine homosexual men from the San Francisco bay area w
Since December 1980, over 2,000 cases of acquired immunodeficiency syndrome (AIDS) have been reported. The charts of 72 patients admitted to the New York University Medical Center with a diagnosis of AIDS were reviewed with particular emphasis on presenting signs, symptoms and laboratory values. Symptoms tended to be
Schweiz Med Wochenschr. 1984 Mar 24;114(12):415-8. Unique Identifier : AIDSLINE MED/84196328
Baumann UA; Anabitarte M
A report is presented on a woman who died of acquired immune deficiency syndrome (AIDS) and her two sexual partners. One of the men had generalised lymphadenopathy and the other severe depression of helper-T-cells with cutaneous anergy, symptoms which may be observed in the prodromal state of AIDS. Apart from regular
Acquired immunodeficiency syndrome, or AIDS, is currently a significant health problem receiving widespread interest as both cause and treatment are sought. Indications are that a transmissible agent is involved. Both clinical and research laboratories are receiving greater numbers of specimens from AIDS patients as b
Hauser GJ; Bino T; Rosenberg H; Zakuth V; Geller E; Spirer Z
The ability of lymphocytes from a patient suffering from the acquired immune deficiency syndrome (AIDS) to produce interleukin-2 ( IL-2 ) was found to be comparable to that of his healthy sex partner and to that of a normal control. Addition of exogenous IL-2 to lymphocy
Natural killer cell activity of peripheral blood mononuclear cells against K562 myeloid cells was studied in 8 normal heterosexual men, 5 healthy homosexual men, and 11 homosexual men with acquired immune deficiency syndrome. The overall natural killer cell activity was lower in healthy homosexual men and in homosexua
EMBO J. 1984 Feb;3(2):327-32. Unique Identifier : AIDSLINE MED/84182493
Nehls P; Rajewsky MF; Spiess E; Werner D
Brain chromosomal DNA isolated from fetal BDIX-rats 1 h after i.v. administration of the ethylating N-nitroso carcinogen N-ethyl-N-nitrosourea (75 micrograms/g body weight), statistically contained one molecule of O6-ethyl-2 -deoxyguanosine (O6-EtdGuo) per 81 micron of DNA, as determined in enzymatic DNA hydrolysates
JAMA. 1984 Jun 8;251(22):2951-5. Unique Identifier : AIDSLINE MED/84188755
Zolla-Pazner S; William D; El-Sadr W; Marmor M; Stahl R
Serum samples from 24 patients with acquired immune deficiency syndrome (AIDS) and from 15 patients with an early or milder form of this disease (suspected AIDS) were found to contain elevated levels of beta 2-microglobulin (beta 2M). Therefore, prospective studies of 40 asymptomatic homosexual men from New York City
Leu HJ; Schneider J; Hardmeier T; Maurer R; Luthy R; Burger R; Burger HR; Krause M
A 48-year-old homosexual with contacts in different countries, including Haiti , presented with multiple pigmented or bluish nodules on both lower legs and upper arms. He had a history of secondary syphilis, hepatitis B and herpes zoster ophthalmicus. Biopsies of the skin tumors reve
This communication concerns a case of endocarditis caused by Corynebacterium diphtheriae. The patient was a 35-year-old male drug addict who was brought to the hospital with fever, chills, and abdominal pain. Two days after admission, blood cultures were found to be growing gram-positive rods suggestive of diphtheroid
In this paper we have attempted to define the role of suppressor T cells in many well-defined murine tumor systems. We have knowingly omitted a blocking antibodies, suppressor B cells as mediators of tumor immunosuppression in various murine tumor systems; these have been well reviewed elsewhere. Also, we have focused
We investigated the possible role of a defect in antigen-presenting cells in the acquired immunodeficiency syndrome (AIDS), by enumeration of Langerhans cells, the epidermal antigen-presenting cells. These cells were stained for the characteristic markers, surface Ia antigen and surface ATPase activity. A significant
Yamaguchi K; Seiki M; Yoshida M; Nishimura H; Kawano F; Takatsuki K
Adult T cell leukemia virus (HTLV or ATLV) proviral DNA integrated in the cellular DNA was examined by a modified Southern blotting method in the peripheral blood mononuclear cells and/or lymph node cells from 61 patients with adult T cell leukemia (ATL) and other hematologic diseases. Serum antibodies against ATL-ass
We report a case of spontaneous perforation of the transverse colon due to multiple ulcerations infected with cytomegalovirus ( CMV ) in a patient suffering from acquired immune deficiency syndrome (AIDS). The authors recommend
Anal warts (condylomata acuminata) from seven homosexual men revealed intraepithelial carcinoma (carcinoma in situ) within the condylomatous tissue or in adjacent anal mucosa. All lesions displayed morphologic evidence of papillomavirus infection and two of the seven revealed histologic changes characteristic of herpe
A human type-C retrovirus, designated HTLV (human T-cell leukemia virus), was isolated from the HTLV producer cell line MT-2. Agarose gel electrophoresis analysis 32P-labeled HTLVMT-2 virion RNA revealed that HTLVMT-2 virion RNA consists mainly of 24S and small amounts of 35S and 32S RNAs. The 24S HTLVMT-2 virion RNA
De Maubeuge J; Mascart-Lemone F; Clumeck N; Jonas C; Panzer JM; Decaux G; Andre J; Goens J; Ledoux-Corbusier M; Achten G
The authors present 2 cases of AIDS revealed by severe recurrent genital herpes simplex. The patients are 2 young, previously healthy, African women without histories of homosexuality or drug abuse. The first patient died after 5 months of follow-up (post mortem findings: viral
Medicine (Baltimore). 1984 May;63(3):155-64. Unique Identifier : AIDSLINE MED/84190601
Lerner CW; Tapper ML
Twenty-five cases of acquired immune deficiency syndrome (AIDS) complicated by opportunistic infections were diagnosed at Lenox Hill Hospital during an 18 month period and followed for at least 1 year or until the patients deaths. Twenty-three patients were homosexual men, including 1 i.v. drug user, and 2 were heter
Nature. 1984 May 17-23;309(5965):276-9. Unique Identifier : AIDSLINE MED/84191556
Chen IS; McLaughlin J; Golde DW
Human T-cell leukaemias and lymphomas associated with the human T-cell leukaemia viruses (HTLV) are invariably neoplasms of cells with mature T-lymphocyte phenotype. Epstein-Barr virus-transformed B- lymphoycte lines which are productively infected with HTLV may be isolated from patients with HTLV malignancies, but no
Proc Natl Acad Sci U S A. 1984 May;81(9):2886-9. Unique Identifier : AIDSLINE MED/84194111
Clapham P; Nagy K; Weiss RA
Pseudotypes of vesicular stomatitis virus (VSV) bearing envelope antigens of human T-cell leukemia virus (HTLV) types 1 and 2 were prepared by propagating VSV in cells lines productively infected with HTLV. Plaque assays of VSV (HTLV) pseudotypes were employed to determine the presence of (i) HTLV receptors on cells a
The light-microscopical, ultrastructural and immunohistochemical findings in the first reported European case of ocular changes in the acquired immuno-deficiency syndrome (AIDS) are presented. The syndrome occurred in a 31-year-old homosexual man who died of Kaposi sarcoma in the skin and internal organs,
Guarda LA; Luna MA; Smith JL Jr; Mansell PW; Gyorkey F; Roca AN
The autopsies of 13 male homosexuals with acquired immune deficiency syndrome (AIDS) were reviewed. All patients had laboratory evidence of cellular immune dysfunction. The most common diagnoses made were disseminated cytomegalovirus infection in 12 patients and Kaposi s sarcoma in
Ann Intern Med. 1984 Jun;100(6):809-15. Unique Identifier : AIDSLINE MED/84201204
Marmor M; Friedman-Kien AE; Zolla-Pazner S; Stahl RE; Rubinstein P; Laubenstein L; William DC; Klein RJ; Spigland I
The cases of 20 male homosexuals with Kaposi s sarcoma and the acquired immunodeficiency syndrome were compared with those of 40 age- and race-matched male homosexual controls. Patients with Kaposi s sarcoma had lower OKT4/OKT8 (T-helper/T-suppressor) ratios than controls, due to smaller numbers of OKT4 cells. Serum I
Lancet. 1984 May 12;1(8385):1033-8. Unique Identifier : AIDSLINE MED/84190310
Mathur-Wagh U; Enlow RW; Spigland I; Winchester RJ; Sacks HS; Rorat E; Yancovitz SR; Klein MJ; William DC; Mildvan D
42 homosexual or bisexual men with persistent generalised lymphadenopathy not attributable to an identifiable cause have been followed longitudinally since February, 1981. Lymphadenopathy was accompanied by fatigue, low-grade fever and/or night sweats (57%), splenomegaly (29%), leucopenia (40%), hypergamma - globulina
Lancet. 1984 May 12;1(8385):1042-6. Unique Identifier : AIDSLINE MED/84190312
Erber WN; Pinching AJ; Mason DY
Immunofluorescence labelling of peripheral blood mononuclear cells is usually done on cells in suspension. This paper describes a procedure based on immuno-alkaline phosphatase staining of routine blood smears. The advantages of this method are that a few drops of blood are sufficient for labelling multiple lymphocyte
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