Toronto : Canadian Gay Archives, c1983 ii, 67 p (Canadian Gay Archives publication ; 7) Unique Identifier : AIDSLINE CAT/8306239
Miller AV
Approximately 1200 references to journal articles, newspaper articles, and a few miscellaneous items published through March, 1983. Arranged according to appearance in the medical press, the gay press, and the popular press. Also covers some foreign titles. Each entry gives bibliographical information. Contains li
An analysis of a prospective study of viral infections in 12 patients with severe combined immunodeficiency is presented. Infections of viral etiology were common, with pulmonary and gastrointestinal infections being most frequent. Fourteen of 25 infections (56%) were nonsocomially acquired and 10 of 25 (40%) were com
S Afr Med J. 1983 Jul 23;64(4):119-22. Unique Identifier : AIDSLINE MED/83249529
Anderson R; Prozesky OW; Eftychis HA; van der Merwe MF; Swanevelder C; Simson IW
Immunological tests of cell-mediated immunity (CMI), serological tests for antibodies to sexually transmitted and possibly immunosuppressive viruses, determination of serum immunoglobulin levels, full blood counts and serotyping for the HLA-DRw5 antigen were performed in 10 homosexual men with a mean age of 35 years (
Crit Care Med. 1983 Jul;11(7):563-73. Unique Identifier : AIDSLINE MED/83233752
Bartlett JG
There have been numerous recent developments in the field of infectious diseases which are relevant to critical care medicine. These include a number of new syndromes, pathogens, and chemotherapeutic modalities. The purpose of this review is to summarize the most significant developments during the past 5 yr which are
Thus, interferon has diverse effects on cellular structure and/or function. Although some of these effects may be involved in interferon s antiviral actions, they may also play a role in normal physiologic processes. Inappropriate production of or response to interferon may, therefore, contribute to abnormal cell-cell
Two patients with hemophilia A had generalized lymphadenopathy, lymphopenia, elevated IgG values, depressed T4 (helper) lymphocytes, elevated T8 (suppressor) lymphocytes, and abnormally low T4/T8 ratios. One of the patients, who also had hepatosplenomegaly, underwent cervical lymph node biopsy; the node contained 43%
Viral transforming (v-onc) genes are derived from cellular (c-onc) genes that are highly conserved among vertebrates. Comparative studies of v-onc and c-onc genes have shed some light on the mechanism leading to formation of the transforming viruses. A specific example of the sis gene is presented here for illustratio
Idiopathic and infective interstitial pneumonitis (IPn) is a common complication after bone marrow transplantation (BMT) in many centers and carries a high mortality. We report here a series of 107 patients with acute leukemia grafted at the Royal Marsden Hospital in which only 11 (10.3%) developed IPn and only 5 died
Sullivan JL; Byron KS; Brewster FE; Baker SM; Ochs HD
The X-linked lymphoproliferative syndrome is characterized by immunodeficiency to Epstein-Barr virus (EBV) manifested by severe or fatal infectious mononucleosis and acquired immunodeficiency. We studied immune responses in six males of a well-characterized kindred with the X-linked lymphoproliferative syndrome. Two m
A total of 1799 swine sera collected in Toyama prefecture in the central part of Japan during the years 1978-82 were tested for antibody against swine influenza virus (SIV), A/New Jersey/8/76 (H1N1). A high prevalence of antibody was observed in the years after the severe epizootic
Groffen J; Heisterkamp N; Stephenson JR; van Kessel AG; de Klein A; Grosveld G; Bootsma D
By analysis of a series of somatic cell hybrids derived by fusion of either mouse or Chinese hamster cells with leukocytes from different chronic myelocytic leukemia (CML) patients or from normal donors, we have localized the human oncogene, c-sis, on the q11 to qter segment of chromosome 22 and demonstrated its trans
A partial amino acid sequence of human platelet-derived growth factor, the major mitogen in serum for cells of mesenchymal origin, has been determined. A region of 104 contiguous amino acids shows virtual identity with the predicted sequence of p28sis, the putative transforming protein of simian sarcoma virus (SSV). T
S Afr Med J. 1983 Jul 23;64(4):140-2. Unique Identifier : AIDSLINE MED/83249534
Ras GJ; Simson IW; Anderson R; Prozesky OW; Hamersma T
This report documents the first 2 cases of the acquired immunodeficiency syndrome in male homosexuals identified in South Africa . Both patients died of Pneumocystis carinii pneumonia and both had cytomegalovirus infection. Neither had periphera
The association of Pneumocystis carinii pneumonia and cytomegalovirus infection in apparently healthy intravenous drug abusers or homosexual males recently has been described. Two patients with this syndrome were seen recently at our institution. Bronchoalveolar lavage samples from
Kaposi s sarcoma (KS), or idiopathic multiple hemorrhagic sarcoma, has heretofore been considered an indolent disease of the elderly, which also occurs in immunosuppressed hosts. Within the last two years, an epidemic of a community-acquired immune deficiency syndrome (AIDS) and disseminated KS has been reported in va
Two hypotheses are presented to explain the recent outbreak of acquired immunodeficiency syndrome (AIDS) and Kaposi s sarcoma in certain risk groups, particularly homosexuals, and the absence of these diseases from other segments of the population. According to the first, AIDS is itself an opportunistic infection. It
Pinching AJ; McManus TJ; Jeffries DJ; Moshtael O; Donaghy M; Parkin JM; Munday PE; Harris JR
97 symptom-free homosexuals were studied clinically, serologically, and with in-vivo and in-vitro tests of cellular immune function in the context of the acquired immunodeficiency syndrome (AIDS). A high proportion of these men showed abnormalities: lymphopenia (33%), decreased T-helper/T-suppressor (Th/Ts) cell ratio
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