Genetic mapping of the mouse proto-oncogene c-sis to chromosome 15. NLM AIDSLINE Important note: Information in this article was accurate in 1983. The state of the art may have changed since the publication date.

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Genetic mapping of the mouse proto-oncogene c-sis to chromosome 15.

Science. 1983 Aug 26;221(4613):867-9. Unique Identifier : AIDSLINE MED/83275728
Kozak CA; Sears JF; Hoggan MD


Abstract: The mouse homolog (c-sis) of the transforming gene of the simian sarcoma virus was mapped to chromosome 15 by the Southern blot analysis of DNA's from hamster-mouse somatic cell hybrids. Alterations in c-sis expression may thus play a role in the various murine neoplastic diseases characterized by rearrangements or duplications of chromosome 15.
Keywords: Animal Chromosome Abnormalities/GENETICS Chromosome Mapping Leukemia, Experimental/*GENETICS Mice Nucleic Acid Hybridization *Oncogenes Retroviridae/*GENETICS Sarcoma Viruses, Simian/*GENETICS JOURNAL ARTICLE

KWDanimalchromosomeabnormalities/geneticschromosomemappingleukemia,experimental/KWDgeneticsmicenucleicacidhybridizationKWDoncogenesretroviridae/KWDgeneticssarcomaviruses,simian/KWDgeneticsjournalarticle
831130
M83B0006


Copyright © 1983 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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