Groopman JE; Ahmed AR; Gottlieb MS; Dept. Hematology/Oncology, Univ. California at Los Angeles, Los; Angeles, CA
The biology of Kaposi s sarcoma (KS) and the relationship of this tumor to the current epidemic of T cell immune deficiency are reviewed. Cytological origins, clinical features, pathogenesis, and therapy of KS are discussed. KS is thought to begin in the mid-dermis and extend to the epidermis. KS is observed in many c
Bouvet E; Institut Leon-M'Ba, Hopital Claude-Bernard, 10, av. de La; Porte-d'Aubervilliers, 75019 Paris, France
Kaposi s sarcoma and opportunistic infections among homosexual men have been well documented by the Center for Disease Control in Atlanta. Opportunistic infections are diverse and are characterized by their severity and recurrences. Kaposi s sarcoma is an angiosarcomatous tumor which evolves rapidly and is characteriz
Ekert H; Dept. Clinical Haematology and Oncology, Royal Children's Hosp.,; Melbourne, Australia
An overview of the practice of clinical hematology and oncology as it occurs in specialized units within general pediatric teaching hospitals is presented. The text reflects a practical approach to the problems encountered in the wards and outpatient clinics. Attempts have been made to integrate pertinent physiology,
Harzmann R; Lower J; Lower R; Bichler KH; Kurth R; Dept. Urology, Univ. Tubingen Medical Sch., Tubingen, W. Germany
Two lines of evidence led to the investigation of human teratocarcinoma cells in vitro for oncogenic retroviruses: the observation by electron microscopy of retrovirus-like particles budding from the syncytial trophoblasts of human placentas, and the demonstration that teratocarcinoma patients before treatment show a
Ann Intern Med. 1982 Dec;97(6):821-5. Unique Identifier : AIDSLINE MED/83072951
Ballow M; Seeley J; Purtilo DT; St. Onge S; Sakamoto K; Rickles FR
A syndrome of chronic mononucleosis occurred in two members of a family. Symptoms were chronic malaise and fatigue; recurrent upper respiratory tract infections; and mild, variable immune abnormalities. Intermittently positive heterophil titers were present for more than 2 years after acute infectious mononucleosis. E
JAMA. 1982 Dec 10;248(22):2980-2. Unique Identifier : AIDSLINE MED/83060071
Zakowski P; Fligiel S; Berlin GW; Johnson L Jr
Five homosexual men dying at UCLA Center for the Health Sciences, Los Angeles, with acquired immunodeficiency and Pneumocystis pneumonia, Kaposi s sarcoma, or cryptosporidiosis since May 1981 have all had mycobacteria of the Mycobacterium avium-intracellulare complex cultured from tissues taken just before death or at
Johns Hopkins Med J. 1982 Nov;151(5):222-30. Unique Identifier : AIDSLINE MED/83060488
Hood AF; Farmer ER; Weiss RA
Kaposi s sarcoma is a multifocal neoplasm of the reticuloendothelial system which has generated great interest recently because of its association with immunosuppressive therapy and its occurrence within a group of homosexual men. Our case demonstrates a relationship between the discontinuation of immunosuppressive th
Ashman RF; White RH; Wiesenhutter C; Cantor Y; Lasarow E; Liebling M; Talal N
Classically, systemic lupus erythematosus (SLE) is a disease of antibody overproduction, whereas the hallmark of acquired immune deficiency is antibody underproduction. Two patients are presented in whom panhypogammaglobulinemia developed during the course of SLE. In both patients, the levels of the major immunoglobul
Closed circular unintegrated DNA of the SEATO strain of gibbon ape leukemia virus (GaLV-S) was isolated from canine thymus fibroblasts after cocultivation with chronically infected bat lung fibroblasts. Restriction endonuclease HindIII cleaves GaLV-S DNA once, thus allowing isolation and cloning of HindIII-digested un
Science. 1982 Dec 10;218(4577):1131-3. Unique Identifier : AIDSLINE GENBANK/J02397
Robbins KC; Devare SG; Reddy EP; Aaronson SA
Simian sarcoma virus (SSV) deletion mutants were constructed from a molecular clone containing the entire infectious provirus. Transfection analysis of these mutants localized the SSV transforming gene to a small region of the viral genome encompassing its cell-derived sequence (v-sis). Antiserum to a peptide synthesi