The acquired immunodeficiency syndrome and Mycobacterium avium-intracellulare bacteremia in a patient with hemophilia. NLM AIDSLINE Important note: Information in this article was accurate in 1983. The state of the art may have changed since the publication date.

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The acquired immunodeficiency syndrome and Mycobacterium avium-intracellulare bacteremia in a patient with hemophilia.

Ann Intern Med. 1983 Mar;98(3):290-3. Unique Identifier : AIDSLINE MED/83150963
Elliott JL; Hoppes WL; Platt MS; Thomas JG; Patel IP; Gansar A

Abstract: A 27-year-old previously healthy man with hemophilia presented with Pneumocystis carinii pneumonia. The patient had several episodes of oral candidiasis followed by disseminated infection with Mycobacterium avium-intracellulare. He was not homosexual nor did he take illicit drugs, but he had been self-administering two to four monthly infusions of factor VIII concentrate for 7 years. In-vitro lymphocyte studies showed findings consistent with the acquired immunodeficiency syndrome that had previously been reported only in homosexual men, drug addicts, and Haitian refugees. The cause of this syndrome is unknown, but the possibility that it is associated with a transmissible agent acquired through the use of blood products such as factor VIII concentrate must be considered.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS/DRUG THERAPY/ *TRANSMISSION Adult Antibodies, Viral/IMMUNOLOGY Case Report Clofazimine/THERAPEUTIC USE Cytomegalovirus/IMMUNOLOGY Hemophilia/*COMPLICATIONS Herpesvirus 4, Human/IMMUNOLOGY Human IgG/IMMUNOLOGY Male Mycobacterium avium/IMMUNOLOGY Mycobacterium Infections/*IMMUNOLOGY Pneumonia, Pneumocystis carinii/*IMMUNOLOGY Thymosin/THERAPEUTIC USE Toxoplasma/IMMUNOLOGY Transfer Factor/THERAPEUTIC USE JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDcomplications/drugtherapy/KWDtransmissionadultantibodies,viral/immunologycasereportclofazimine/therapeuticusecytomegalovirus/immunologyhemophilia/KWDcomplicationsherpesvirus4,human/immunologyhumanigg/immunologymalemycobacteriumavium/immunologymycobacteriuminfections/KWDimmunologypneumonia,pneumocystiscarinii/KWDimmunologythymosin/therapeuticusetoxoplasma/immunologytransferfactor/therapeuticusejournalarticle
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Copyright © 1983 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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