Relation between sexual practices and T-cell subsets in homosexually active men. NLM AIDSLINE Important note: Information in this article was accurate in 1983. The state of the art may have changed since the publication date.

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Relation between sexual practices and T-cell subsets in homosexually active men.

Lancet. 1983 Mar 19;1(8325):609-11. Unique Identifier : AIDSLINE MED/83140377
Detels R; Fahey JL; Schwartz K; Greene RS; Visscher BR; Gottlieb MS

Abstract: 27% of 89 young, non-ill, homosexually active men in Los Angeles had a Leu-3(OKT4)/Leu-2(OKT8) ratio less than or equal to 0 . 8. The low ratio was due to a significantly raised mean number of Leu-2 cells, whereas individuals with acquired immune deficiency syndrome had a decrease in both Leu-3 and Leu-2 cells. The term acquired immune augmentation may be appropriate for those with a low ratio due to raised numbers of Leu-2 cells. Those practising passive (receptive) anal intercourse had a significantly higher mean number of Leu-2 cells than did those practising only active (insertive) anal intercourse or no anal intercourse. The results of this study suggest that two distinct conditions occur in homosexually active men. Whether acquired immune augmentation is a precursor of the rarer acquired immune deficiency syndrome or is an unrelated disorder needs to be determined. In this study passive anal intercourse was associated with acquired immune augmentation.
Keywords: Acquired Immunodeficiency Syndrome/*DIAGNOSIS/IMMUNOLOGY Adult Age Factors Chronic Disease Diagnosis, Differential *Homosexuality Human Intestinal Mucosa/INJURIES Lymphatic Diseases/DIAGNOSIS/*IMMUNOLOGY Male Rectum/INJURIES *Sex Behavior Support, U.S. Gov't, P.H.S. T-Lymphocytes/ANALYSIS/*IMMUNOLOGY JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDdiagnosis/immunologyadultagefactorschronicdiseasediagnosis,differentialKWDhomosexualityhumanintestinalmucosa/injurieslymphaticdiseases/diagnosis/KWDimmunologymalerectum/injuriesKWDsexbehaviorsupport,uKWDsKWDgov't,pKWDhKWDsKWDt-lymphocytes/analysis/KWDimmunologyjournalarticle
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Copyright © 1983 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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