Thromb Haemost. 1982 Dec 27;48(3):250-2. Unique Identifier : AIDSLINE MED/83146917
Vercellotti GM; Mosher DF
A variety of coagulation abnormalities has been described in systemic lupus erythematosus (SLE). We report a unique SLE patient with an acquired factor XI deficiency. The low factor XI levels were not due to a classical coagulation inhibitor, but to a plasma factor (probably an immunoglobulin) that selectively bound f
Jones JF; Minnich LM; Lucas DO; Fulginiti VA; Ingham Z; Langford MP; Stanton GJ
Two Navajo Indian children with severe combined immunodeficiency disease (SCID) lost reconstituted immune function after virus infections. A serum factor which inhibited normal lymphocyte response to mitogens was found in one of them and led to the examination of sera from five other Navajos with SCID. Mean inhibition
Schweiz Med Wochenschr. 1983 Jan 8;113(1):28-30. Unique Identifier : AIDSLINE MED/83146289
Thornton E; Vollenweider M; Hirschel B
Case report on a 49-year-old woman who contracted acute hepatitis B during a trip to Haiti in 1977. The hepatitis healed and the patient was in good health until July 1982 when she died of pneumocystis carinii pneumonia despite early treatment. This case resembles the acquired immun
In the past two years there has been an unprecedented outbreak of Kaposi s sarcoma (KS) among male homosexuals with idiopathic acquired cellular immunodeficiency. A homosexual patient is presented in whom KS was first recognized in the lung. Pulmonary presentation of KS has not been previously reported in this group o
Between September 1981 and June 1982, the acquired immunodeficiency syndrome and Pneumocystis carinii pneumonia were diagnosed in seven previously healthy young men incarcerated for 5 to 38 months in New York State correctional facilities. All seven patients were anergic, six were lymphopenic, and all developed oral c
Am J Med. 1983 Mar;74(3):433-41. Unique Identifier : AIDSLINE MED/83149915
Small CB; Klein RS; Friedland GH; Moll B; Emeson EE; Spigland I
Fourteen previously healthy young patients with unusual community-acquired opportunistic infections were seen over a period of three years. They differ from patients previously described in that 11 were heterosexual drug abusers (including two women) and only three were homosexual men. There were eight Puerto Ricans,
Proc Natl Acad Sci U S A. 1983 Feb;80(3):731-5. Unique Identifier : AIDSLINE GENBANK/J02394
Devare SG; Reddy EP; Law JD; Robbins KC; Aaronson SA
The complete nucleotide sequence of the proviral genome of simian sarcoma virus (SSV), an acute transforming retrovirus of primate origin, has been determined. Like other transforming viruses, SSV contains sequences derived from its helper virus, simian sarcoma-associated virus (SSAV), and a cell-derived (v-sis) inser
Twenty Haitian patients, hospitalized from 1 April 1980 to 20 June 1982, had Pneumocystis carinii pneumonia, central nervous system toxoplasmosis, esophageal candidiasis, cryptococcosis, disseminated cytomegalovirus , progressive herpes simplex virus, chronic enteric coccidiosis, or
A patient with hemophilia A developed T-cell deficiency characterized by infection with several opportunistic pathogens. Immunologic investigation showed cutaneous anergy, lymphocyte unresponsiveness to mitogens and antigens, an abnormal ratio of T-helper and T-suppressor cells with absolute lymphopenia and elevated I
Ann Intern Med. 1983 Mar;98(3):287-90. Unique Identifier : AIDSLINE MED/83150962
Poon MC; Landay A; Prasthofer EF; Stagno S
A previously healthy patient with classic hemophilia who was on a home infusion program with factor VIII concentrates developed an acquired immunodeficiency syndrome manifested by a dramatic weight loss (47 kg over 12 months), lassitude, transient thrombocytopenia, and opportunistic infections with Varicella zoster, P
Ann Intern Med. 1983 Mar;98(3):290-3. Unique Identifier : AIDSLINE MED/83150963
Elliott JL; Hoppes WL; Platt MS; Thomas JG; Patel IP; Gansar A
A 27-year-old previously healthy man with hemophilia presented with Pneumocystis carinii pneumonia. The patient had several episodes of oral candidiasis followed by disseminated infection with Mycobacterium avium-intracellulare. He was not homosexual nor did he take illicit drugs, but he had been self-administering tw
Antibodies cross-reactive with type C viral p30 were concentrated from 105 samples of human plasma by affinity chromatography using Sepharose beads to which disrupted Simian sarcoma associated virus (SSAV) had been coupled. Eluates obtained from the affinity beads were tested for anti-p30 activity by performing radio-
White retinal opacities and ocular inflammation may be two of the early signs of a new syndrome of acquired immunodeficiency. This syndrome primarily affects young homosexual men and is characterized by acquired cellular immunodeficiency in infections with multiple opportunistic microorganisms in addition to Kaposi s
Lancet. 1983 Mar 5;1(8323):503-5. Unique Identifier : AIDSLINE MED/83140288
Luban NL; Kelleher JF Jr; Reaman GH
Acquired immunodeficiency syndrome (AIDS) is a disease of unknown aetiology characterised by opportunistic infections, unusual malignancies, and aberrations in cellular immunity; lymphopenia and reversal of helper/suppressor T-cell ratios are the most common. In this study the immune function in 25 children and adoles
Lancet. 1983 Mar 19;1(8325):609-11. Unique Identifier : AIDSLINE MED/83140377
Detels R; Fahey JL; Schwartz K; Greene RS; Visscher BR; Gottlieb MS
27% of 89 young, non-ill, homosexually active men in Los Angeles had a Leu-3(OKT4)/Leu-2(OKT8) ratio less than or equal to 0 . 8. The low ratio was due to a significantly raised mean number of Leu-2 cells, whereas individuals with acquired immune deficiency syndrome had a decrease in both Leu-3 and Leu-2 cells. The te
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