Immune deficiency syndrome in children. NLM AIDSLINE Important note: Information in this article was accurate in 1983. The state of the art may have changed since the publication date.

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Immune deficiency syndrome in children.

JAMA. 1983 May 6;249(17):2345-9. Unique Identifier : AIDSLINE MED/83164649
Oleske J; Minnefor A; Cooper R Jr; Thomas K; dela Cruz A; Ahdieh H; Guerrero I; Joshi VV; Desposito F

Abstract: The present epidemic of acquired immune deficiency syndrome (AIDS) was originally described in homosexual men and subsequently in intravenous drug abusers, Haitians, and hemophiliacs. Profound defects in cell-mediated immunity (CMI) are associated with Kaposi's sarcoma and a variety of serious opportunistic infections. Recently, we and others have encountered a group of children with an otherwise unexplained immune deficiency syndrome and infections of the type found in adults with AIDS. In this report, we describe eight children from the Newark, NJ, metropolitan area born into families with recognized risks for AIDS. These patients have had recurrent febrile illnesses, failure to thrive, hypergammaglobulinemia, and depressed CMI. Four of these children have died. Our experience suggests that children living in high-risk households are susceptible to AIDS and that sexual contact, drug abuse, or exposure to blood products is not necessary for disease transmission.
Keywords: Acquired Immunodeficiency Syndrome/*EPIDEMIOLOGY/MORTALITY/ TRANSMISSION Age Factors Case Report Child, Preschool Environmental Exposure Female Haiti/ETHNOLOGY Human Infant Male New Jersey Pregnancy Prenatal Exposure Delayed Effects Prostitution Risk Substance Abuse JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/
830730
M8370045

Copyright © 1983 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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