Ziehl-Neelsen (acid-fast) and Giemsa-stained microscopic sections of enlarged cervical lymph nodes obtained from a 39 year-old male homosexual with acquired immunodeficiency syndrome (AIDS) were studied for the presence of cell wall-deficient bacteria. Intra- and extra-cellular, variably acid-fast forms were observed
Uremia is a metabolic imbalance accompanied by an acquired immunologic deficiency state. Fatal infections frequently met with uremia may be explained both by cellular and humoral immunologic disorders. In this article, the cellular immune status was investigated via intradermal skin test, and the serum and cerebrospin
JAMA. 1983 May 6;249(17):2345-9. Unique Identifier : AIDSLINE MED/83164649
Oleske J; Minnefor A; Cooper R Jr; Thomas K; dela Cruz A; Ahdieh H; Guerrero I; Joshi VV; Desposito F
The present epidemic of acquired immune deficiency syndrome (AIDS) was originally described in homosexual men and subsequently in intravenous drug abusers, Haitians, and hemophiliacs. Profound defects in cell-mediated immunity (CMI) are associated with Kaposi s sarcoma and a variety of serious opportunistic infections
Am J Med. 1983 Apr;74(4):652-6. Unique Identifier : AIDSLINE MED/83175695
Volberding P; Conant MA; Stricker RB; Lewis BJ
Kaposi s sarcoma has recently appeared in an aggressive form in young, previously healthy, homosexual men. The disease in these patients corresponds most closely to disseminated Kaposi s sarcoma common in areas of Africa. This and the underlying acquired immune deficiency in the current patients in the
Post MJ; Chan JC; Hensley GT; Hoffman TA; Moskowitz LB; Lippmann S
The clinical data, histologic findings, and computed tomographic (CT) abnormalities in eight adult Haitians with toxoplasma encephalitis were analyzed retrospectively. Diagnosis was established by identification of Toxoplasma gondii on autopsy in five and brain biopsy in three specimens and subsequently confirmed by t
Several combinations of F1 hybrid mice were injected intravenously with parental spleen cells to determine the minimal H-2 differences between F1 and parent that are necessary to induce graft-vs.-host-associated immune suppression (GVH-associated suppression). 7-14 d after injection, the spleens of the F1 mice were te
JAMA. 1983 May 6;249(17):2350-6. Unique Identifier : AIDSLINE MED/83164650
Rubinstein A; Sicklick M; Gupta A; Bernstein L; Klein N; Rubinstein E; Spigland I; Fruchter L; Litman N; Lee H; Hollander M
A new syndrome of acquired immunodeficiency has been identified in seven children who were small for gestational age at birth and subsequently have exhibited failure to thrive, lymphadenopathy, parotitis, hepatosplenomegaly, interstitial pneumonia, and recurrent infections. All have a profound cell-mediated immunodefi
The immunocompromise syndrome in homosexual men in the USA is thought to be associated with cytomegalovirus ( CMV ) infection and nitrite intake. Such men often have a lymphopenia. In a clinic in London 76% of 46 unselected hom
JAMA. 1983 May 6;249(17):2370-4. Unique Identifier : AIDSLINE MED/83164654
Sonnabend J; Witkin SS; Purtilo DT
The acquired immunodeficiency syndrome (AIDS) occurs in a subgroup of male homosexuals having sexual contact with a large number of partners. Uncommonly, AIDS has also been diagnosed in Haitians, hemophiliacs, and intravenous drug users and their infants. Manifestations include autoimmune disturbances, opportunistic i
Cytomegalovirus ( CMV ) is a ubiquitous agent that causes infection in all age-groups. Fortunately, the infection is usually asymptomatic, and thus it goes unnoticed. It can, however, have serious sequelae in affected neonates. One of the most significant new deve
Polybrene was shown to enhance the adsorption of simian sarcoma virus-simian sarcoma associated virus complex (SSV-1/SSAV-1) and baboon endogenous virus (BaEV) onto cells in culture. A 16- to 18-fold increased adsorption of both viruses occurred at 8 micrograms/ml polybrene within one hour after infection. The polybre
Ammann AJ; Cowan MJ; Wara DW; Weintrub P; Dritz S; Goldman H; Perkins HA
An infant who received multiple transfusions during the first few days of life for rhesus disease became ill with recurrent infections when 6 months old. Hepatitis, thrush , Candida dermatitis, otitis media, and disseminated Mycobacterium avium intracellulare infection occurred
In earlier experiments we had noted that transformed and leukemic leukocytes produced an RNA-rich angiogenic lymphokine. The formation of capillaries is a stepwise process in which reticulum cells first become detached and attracted to a site (mobilization and migration along a reticulin network). This is followed by